Patents Assigned to Laboratoires Thea
  • Patent number: 11369519
    Abstract: Disclosed is an eye mask adapted to cover the eyes and the eyelids of a user. The mask includes a main body including an electrical heater and a battery configured to supply the electrical heater and a removable member removably linked to the main body. The removable member includes a wall forming a reservoir provided with retaining orifices adapted to retain a liquid, in particular water, under the effect of the surface tension between the liquid and walls of the orifices. Also disclosed is a method of using such a mask.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: June 28, 2022
    Assignee: LABORATOIRES THEA
    Inventor: Edmund Thomas Fuller
  • Patent number: 10881638
    Abstract: Ophthalmic nutraceutical composition comprising: vitamins; trace elements; carotenoids; omega-3 fatty acids; and resveratrol.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: January 5, 2021
    Assignee: LABORATOIRES THEA
    Inventors: Céline Olmiere, Fabrice Mercier
  • Patent number: 9402765
    Abstract: The present invention relates to a bottle for packaging a liquid to be distributed drop by drop comprising a reservoir the walls of which can be reversibly elastically deformed by letting air into the container, surmounted by a liquid dispensing head comprising a dropper nozzle protruding from the bottle and an anti-bacterial filter membrane, that is partially hydrophilic and partially hydrophobic, interposed across the path of the liquid and the air, at the base of the said nozzle. In the dispensing head, the proposal is to create the nozzle by itself out of a material containing a bactericidal agent that has the effect of preventing any bacterial growth on the surface of the said nozzle on the outside of the antibacterial membrane. A porous core is advantageously positioned inside the duct through which liquid is expelled and air is admitted.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: August 2, 2016
    Assignee: LABORATOIRES THEA
    Inventors: Jean-Frederic Chibret, Alain Defemme, Michel Faurie, Fabrice Mercier
  • Patent number: 9289399
    Abstract: The invention concerns a pharmaceutical composition characterized in that it contains a combination of a parasympatholytic agent, a sympathomimetic agent and a local anaesthetic. Such a composition may be injected into the anterior chamber of the eye before a cataract operation or instilled on the eye before laser treatment.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: March 22, 2016
    Assignee: LABORATOIRES THEA
    Inventor: Walid Khatib
  • Patent number: 9174777
    Abstract: The invention relates to a bottle for packaging a liquid with dropper delivery comprising a reservoir with an elastically deformable wall that can be reversed by letting air into the receptacle, surmounted by a dispensing head for the liquid comprising a drop-counting end-piece protruding to the outside of the bottle and an anti-bacterial filtering membrane, made partially hydrophilic and partially hydrophobic, which is interposed across the path of the liquid and of the air, at the base of the said end-piece. The dispensing head comprises an insert with a recessed body which contains a porous pad regulating the flow of liquid placed downstream of the reservoir and upstream of a chamber delimited downstream of the said membrane. At the base of this insert on the inner side of the bottle, longitudinal arches supporting a central pellet make star-shaped passageways radially guiding the air that enters the bottle after having passed through the porous pad.
    Type: Grant
    Filed: February 3, 2011
    Date of Patent: November 3, 2015
    Assignee: LABORATOIRES THEA
    Inventors: Alain Defemme, Fabrice Mercier
  • Publication number: 20150284173
    Abstract: The invention concerns a liquid dispenser head which is designed to be mounted on a bottle containing a liquid and comprises a filtering device (26) forming an interface between the inside and the outside of the bottle. The filtering device comprises tubular filters (30) which are extended longitudinally so they can be plunged into the bottle, particularly tubular filters whose wall consists of a membrane that is selectively permeable to a liquid to be expelled from the bottle and made of hydrophilic material for this purpose. So that the expelled liquid can be replaced by air, the membrane forming the wall of said filter tube is made of hydrophobic material so as to be selectively air-permeable. The hydrophobic membrane also filters bacteria in the air.
    Type: Application
    Filed: August 6, 2013
    Publication date: October 8, 2015
    Applicant: LABORATOIRES THEA
    Inventors: Alain Defemme, Fabrice Mercier
  • Patent number: 8894622
    Abstract: The present invention relates to a bottle for packaging a liquid to be distributed drop by drop comprising a reservoir the walls of which can be reversibly elastically deformed by letting air into the container, surmounted by a liquid dispensing head comprising a dropper nozzle protruding from the bottle and an anti-bacterial filter membrane, that is partially hydrophilic and partially hydrophobic, interposed across the path of the liquid and the air, at the base of the said nozzle. In the dispensing head, the proposal is to create the nozzle by itself out of a material containing a bactericidal agent that has the effect of preventing any bacterial growth on the surface of the said nozzle on the outside of the antibacterial membrane. A porous core is advantageously positioned inside the duct through which liquid is expelled and air is admitted.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: November 25, 2014
    Assignee: Laboratoires Thea
    Inventors: Jean-Frédéric Chibret, Alain Defemme, Michel Faurie, Fabrice Mercier
  • Patent number: 8772337
    Abstract: The present invention provides an ophthalmic solution without an antimicrobial preservative. The solution includes as an active substance at least one prostaglandin and as a solubilizing agent, a surfactant, where the solubilizing agent is polyoxyl-15-hydroxystearate.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: July 8, 2014
    Assignee: Laboratoires Thea
    Inventors: Frederic Pilotaz, Fabrice Mercier, Henri Chibret
  • Patent number: 8690019
    Abstract: A head for dispensing liquid as a drip, includes a nozzle onto which a channel for ejecting the liquid leads. Air sucked in from the outside is returned through the channel in the opposite direction. In the nozzle, on the ejection channel, the drip dispensing head of the invention includes a valve functioning as a non-return valve for the circulation of the liquid being ejected. A mobile disc of the valve is produced so as to selectively enable air to pass through the valve when the disc is bearing against the seat thereof in a position for closing the liquid ejection channel. The disc is returned to the position by negative pressure applied upstream, which tends to suck in outside air. The disc is advantageously made of a microporous material, which provides antibacterial filtering of the return air.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: April 8, 2014
    Assignee: Laboratoires Thea
    Inventors: Alain Defemme, Fabrice Mercier
  • Patent number: 8663678
    Abstract: A solid dosage form for the ocular administration of an active principle includes at least one biocompatible, water-soluble excipient for ophthalmic use. The form is obtained using a method which is selected from among the following: direct compression, dry compression, wet compression, compression of a lyophilizate, the compression being carried out a temperature below 45° C., or lyophilization, such that the form can disintegrate and release the active principle in the conjunctival sac. The invention also relates to an ophthalmic insert having the aforementioned dosage form which is appropriately dimensioned for ocular administration.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: March 4, 2014
    Assignee: Laboratoires Thea
    Inventors: Saïd El Meski, Philippe Tourrette, Jean-Marc Aiache, Marie Di Battista, Gilbert Serpin
  • Patent number: 8637054
    Abstract: This invention concerns an ophthalmic solution including: at least one prostaglandin; a solubilizing agent; a gelling agent of the carbomer type; a carbomer polymerization-inhibiting agent; a co-gelling/co-solubilizing agent.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: January 28, 2014
    Assignee: Laboratoires Thea
    Inventor: Fabrice Mercier
  • Publication number: 20130267472
    Abstract: This invention concerns an aqueous ophthalmic solution containing an immunosuppressive agent, such as cyclosporin A, and at least three polymers. The three polymers are preferably a combination of a cellulose derivative, a polyvinyl derivative, and a macrogolglycerol hydroxystearate.
    Type: Application
    Filed: March 12, 2013
    Publication date: October 10, 2013
    Applicant: LABORATOIRES THEA
    Inventors: Emmanuel Muriaux, Fabrice Mercier
  • Patent number: 8397927
    Abstract: The break-open valve (1) for a container (21) comprises a break-away element (4) which can be twisted off by turning an activator (3). The valve (1) can be used for hermetically sealing a container (21) until its first opening and also for making it tamper-evident. The activator (3) is rotatably affixed to the valve head (2). The activator (3) comprises an inserted disk (16) with at least one opening (10) and a socket (5) which engages the break-away element (4). The activator (3) further comprises a membrane (17) which protects the contents within the activator (3) from contaminants entering through spout (18). The valve (1) has the advantage that it is cost efficient in its production, that it is easy to use and that it is suitable for dispensing sterile contents in more than one dose.
    Type: Grant
    Filed: August 25, 2005
    Date of Patent: March 19, 2013
    Assignee: Laboratoires Thea
    Inventor: Daniel Krebs
  • Publication number: 20120322871
    Abstract: This invention concerns an ophthalmic solution including: at least one prostaglandin; a solubilizing agent; a gelling agent of the carbomer type; a carbomer polymerization-inhibiting agent; a co-gelling/co-solubilizing agent.
    Type: Application
    Filed: August 27, 2012
    Publication date: December 20, 2012
    Applicant: Laboratoires Thea
    Inventor: Fabrice Mercier
  • Publication number: 20120310185
    Abstract: The invention relates to a bottle for packaging a liquid with dropper delivery comprising a reservoir with an elastically deformable wall that can be reversed by letting air into the receptacle, surmounted by a dispensing head for the liquid comprising a drop-counting end-piece protruding to the outside of the bottle and an anti-bacterial filtering membrane, made partially hydrophilic and partially hydrophobic, which is interposed across the path of the liquid and of the air, at the base of the said end-piece. The dispensing head comprises an insert with a recessed body which contains a porous pad regulating the flow of liquid placed downstream of the reservoir and upstream of a chamber delimited downstream of the said membrane. At the base of this insert on the inner side of the bottle, longitudinal arches supporting a central pellet make star-shaped passageways radially guiding the air that enters the bottle after having passed through the porous pad.
    Type: Application
    Filed: February 3, 2011
    Publication date: December 6, 2012
    Applicant: Laboratoires Thea
    Inventors: Alain Defemme, Fabrice Mercier
  • Publication number: 20110319487
    Abstract: This invention concerns an ophthalmic solution including: at least one prostaglandin; a solubilizing agent; a gelling agent of the carbomer type; a carbomer polymerization-inhibiting agent; a co-gelling/co-solubilizing agent.
    Type: Application
    Filed: June 28, 2011
    Publication date: December 29, 2011
    Applicant: Laboratoires THEA
    Inventor: Fabrice Mercier
  • Publication number: 20100210720
    Abstract: The present invention provides an ophthalmic solution without an antimicrobial preservative. The solution includes as an active substance at least one prostaglandin and as a solubilizing agent, a surfactant, where the solubilizing agent is polyoxyl-15-hydroxystearate.
    Type: Application
    Filed: July 17, 2008
    Publication date: August 19, 2010
    Applicant: LABORATOIRES THEA
    Inventors: Frederic Pilotaz, Fabrice Mercier, Henri Chibret
  • Publication number: 20080194649
    Abstract: The invention concerns a pharmaceutical composition characterised in that it contains a combination of a parasympatholytic agent, a sympathomimetic agent and a local anaesthetic. Such a composition may be injected into the anterior chamber of the eye before a cataract operation or instilled on the eye before laser treatment.
    Type: Application
    Filed: March 9, 2006
    Publication date: August 14, 2008
    Applicant: LABORATOIRES THEA
    Inventor: Walild Khatib
  • Patent number: 6336571
    Abstract: The invention concerns a device comprising a flask (1) with variable internal volume having a rigid neck (5) wherein is arranged the body (3) of a dispensing head (2) ending in a conduit (41) discharging the liquid and containing a microporous pad (6) for generating a head loss regulating the liquid flow pushed therethrough into a distribution chamber (31) communicating with said conduit. The pad is advantageously made of a material inert with respect to the liquid and combined with an antibacterial filtering element (9) preventing outside air from entering the flask. It evenly occupies the body (3) over the whole cross-section of the liquid passage.
    Type: Grant
    Filed: May 3, 2000
    Date of Patent: January 8, 2002
    Assignee: Laboratoires Thea S.A.
    Inventors: Henri Chibret, Michel Faurie, Jacques Luyckx, Alain Defemme, Thierry Coquel