Abstract: A method for acquiring a digital image of an agglutination result comprising performing an agglutination assay on a reaction substrate having a set of dimensions and characteristics which permit a pattern of agglutination in a result of said assay. The image of the result is developed. The image has a colored background which maximizes a signal to noise ratio. Further, the image has been passed through a filter that complements an action of the colored background and enhances the agglutinates in the image while additionally increasing the signal to noise ratio.