Patents Assigned to Laboratories Lesvi, S.L.
  • Stable micronised monoclin form of asenapine maleate and its synthesis
    Patent number: 9505771
    Abstract: A stable micronized monoclinic form of asenapine maleate is described, which comprises 5% by weight or less of orthorhombic form or any other crystalline form of asenapine maleate, wherein the asenapine maleate has a particle size distribution characterized by a d90 equal to or below 40 ?m. Processes for preparing the stable micronized monoclinic form of asenapine maleate are also described. Formula (I).
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: November 29, 2016
    Assignee: Laboratories Lesvi S.L.
    Inventors: Agusti Bertran, Josep Terradas
  • Process for the preparation of asenapine
    Patent number: 8653280
    Abstract: The present invention is directed to novel compounds of formula (I) as well as to the process for their preparation. Novel compounds of formula (I) can be converted into asenapine through an efficient process. The invention also relates to novel intermediates used in this process and their use in the preparation of compounds of formula (I).
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: February 18, 2014
    Assignee: Laboratories Lesvi, S.L.
    Inventors: Pere Dalmases Barjoan, Juan Huguet Clotet, Jordi Peirats Masia