Abstract: The present invention concerns therapeutic compositions containing proteins that are the variable regions of IgNAR immunoglobulins, denominated vNAR, that specifically bind and neutralizes cytokines involved in a diversity of process such as inflammation and neovascularization, its ability to reach, bind, and neutralize the activity of one antigenic molecule localized in an immunoprivileged organs, are also described.
Type:
Grant
Filed:
July 17, 2013
Date of Patent:
July 26, 2016
Assignee:
LABORATORIES SILANES S.A. DE C.V.
Inventors:
Jorge F. Paniagua-Solís, María Teresa Mata-González, Walter J. García-Ubbelohde, Araceli Olguín-Jimenez, Alexei F. Licea-Navarro, Tanya A. Camacho-Villegas, Edna Sanchez-Castrejon