Patents Assigned to Laboratories Thea
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Patent number: 11116694Abstract: The invention relates to a device for dispensing an aqueous liquid through an interface membrane made partially hydrophilic and partially hydrophobic, made so that when in operation, during each operation of dispensing a metered amount of liquid, the streams of air and liquid flow alternately in a capillary channel (18) downstream from the membrane. Said interface membrane (7) is made of a filtering material which includes biocidal metal cations in the body thereof. Said device comprises a porous insert (8), which is permeable both to liquid and to air, which is arranged upstream from the membrane in the path of the fluids and which is made of a material including sites with negative charges capable of attracting biocidal metal cations from said membrane.Type: GrantFiled: March 31, 2016Date of Patent: September 14, 2021Assignee: LABORATORIES THEAInventors: Alain Defemme, Fabrice Mercier
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Patent number: 10857067Abstract: The invention proposes a biological protection membrane which is mounted, in a device for dispensing liquid from a sterile packaging bottle, across a fluid-circulation duct, in the path of the liquid extracted from the bottle and the outside air which is drawn into the bottle. The membrane (7) is made partially of a hydrophilic material and partially of a hydrophobic material. Both the hydrophobic portion (23) and the hydrophilic portion (22) are made from a polymer base, laden in the body thereof with a biocidal agent that is active in the destruction of bacteria by the ionic oxidation effect. The circulation of fluids through the membrane (7) is organised so as to promote the ionic action on the flow of outside air in the hydrophobic material, and to drive the ionically charged active agent by the liquid passing through the membrane in the hydrophilic portion thereof.Type: GrantFiled: March 31, 2015Date of Patent: December 8, 2020Assignee: Laboratories TheaInventors: Alain Defemme, Fabrice Mercier
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Patent number: 9949872Abstract: An eye and eyelid cover includes a pair of spaced viewing windows between which, in use, a reservoir of hot water is contained, and a compartment within which a phase change material is contained, the phase change material being molten at the initial temperature of the hot water and solidifying during cooling of the hot water while a treatment procedure is being carried out.Type: GrantFiled: February 21, 2012Date of Patent: April 24, 2018Assignee: LABORATORIES THEAInventor: Edmund Thomas Fuller
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Publication number: 20180078456Abstract: The invention proposes a biological protection membrane which is mounted, in a device for dispensing liquid from a sterile packaging bottle, across a fluid-circulation duct, in the path of the liquid extracted from the bottle and the outside air which is drawn into the bottle. The membrane (7) is made partially of a hydrophilic material and partially of a hydrophobic material. Both the hydrophobic portion (23) and the hydrophilic portion (22) are made from a polymer base, laden in the body thereof with a biocidal agent that is active in the destruction of bacteria by the ionic oxidation effect. The circulation of fluids through the membrane (7) is organised so as to promote the ionic action on the flow of outside air in the hydrophobic material, and to drive the ionically charged active agent by the liquid passing through the membrane in the hydrophilic portion thereof.Type: ApplicationFiled: March 31, 2015Publication date: March 22, 2018Applicant: Laboratories TheaInventors: Alain DEFEMME, Fabrice MERCIER
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Publication number: 20180078455Abstract: The invention relates to a device for dispensing an aqueous liquid through an interface membrane made partially hydrophilic and partially hydrophobic, made so that when in operation, during each operation of dispensing a metered amount of liquid, the streams of air and liquid flow alternately in a capillary channel (18) downstream from the membrane. Said interface membrane (7) is made of a filtering material which includes biocidal metal cations in the body thereof. Said device comprises a porous insert (8), which is permeable both to liquid and to air, which is arranged upstream from the membrane in the path of the fluids and which is made of a material including sites with negative charges capable of attracting biocidal metal cations from said membrane.Type: ApplicationFiled: March 31, 2016Publication date: March 22, 2018Applicant: Laboratories TheaInventors: Alain DEFEMME, Fabrice MERCIER
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Patent number: 9487339Abstract: The invention concerns a liquid dispenser head which is designed to be mounted on a bottle containing a liquid and comprises a filtering device (26) forming an interface between the inside and the outside of the bottle. The filtering device comprises tubular filters (30) which are extended longitudinally so they can be plunged into the bottle, particularly tubular filters whose wall consists of a membrane that is selectively permeable to a liquid to be expelled from the bottle and made of hydrophilic material for this purpose. So that the expelled liquid can be replaced by air, the membrane forming the wall of said filter tube is made of hydrophobic material so as to be selectively air-permeable. The hydrophobic membrane also filters bacteria in the air.Type: GrantFiled: August 6, 2013Date of Patent: November 8, 2016Assignee: Laboratories TheaInventors: Alain Defemme, Fabrice Mercier
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Publication number: 20150150719Abstract: The present invention relates to a bottle for packaging a liquid to be distributed drop by drop comprising a reservoir the walls of which can be reversibly elastically deformed by letting air into the container, surmounted by a liquid dispensing head comprising a dropper nozzle protruding from the bottle and an anti-bacterial filter membrane, that is partially hydrophilic and partially hydrophobic, interposed across the path of the liquid and the air, at the base of the said nozzle. In the dispensing head, the proposal is to create the nozzle by itself out of a material containing a bactericidal agent that has the effect of preventing any bacterial growth on the surface of the said nozzle on the outside of the antibacterial membrane. A porous core is advantageously positioned inside the duct through which liquid is expelled and air is admitted.Type: ApplicationFiled: October 30, 2014Publication date: June 4, 2015Applicant: LABORATORIES THEAInventors: Jean-Frederic CHIBRET, Alain DEFEMME, Michel FAURIE, Fabrice MERCIER
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Patent number: 8969305Abstract: Described herein is an aqueous ophthalmic solution containing an immunosuppressive agent, such as cyclosporin A, and at least three polymers. The three polymers are preferably a combination of a cellulose derivative, a polyvinyl derivative, and a macrogolglycerol hydroxystearate.Type: GrantFiled: March 12, 2013Date of Patent: March 3, 2015Assignee: Laboratories TheaInventors: Emmanuel Muriaux, Fabrice Mercier
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Publication number: 20140364927Abstract: An eye and eyelid cover includes a pair of spaced viewing windows between which, in use, a reservoir of hot water is contained, and a compartment within which a phase change material is contained, the phase change material being molten at the initial temperature of the hot water and solidifying during cooling of the hot water whilst a treatment procedure is being carried out.Type: ApplicationFiled: February 21, 2012Publication date: December 11, 2014Applicants: LABORATORIES THEAInventor: Edmund Thomas Fuller
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Patent number: 7971755Abstract: The invention concerns a container for packaging a liquid (1) to be dispensed in drops. The container is reversibly deformable by air input and is equipped with a head (3) for dispensing liquid through a nozzle (5). The dispensing head (3) comprises a recessed body (4) which is nested inside a neck (10) of the container and which holds a hydrophobic microporous pad (8) arranged upstream of a chamber (9). Chamber (9) is provided with an air reservoir for preventing the liquid from passing through the microporous pad (8) between two liquid dispensing operations, when the nozzle (5) is sealingly obstructed with a cap (6), and for drying a partly hydrophilic and hydrophobic filtering membrane (7) arranged in the dispensing head (3).Type: GrantFiled: June 24, 2005Date of Patent: July 5, 2011Assignee: Laboratories TheaInventor: Michel Faurie
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Publication number: 20110125111Abstract: The present invention relates to a bottle for packaging a liquid to be distributed drop by drop comprising a reservoir the walls of which can be reversibly elastically deformed by letting air into the container, surmounted by a liquid dispensing head comprising a dropper nozzle protruding from the bottle and an anti-bacterial filter membrane, that is partially hydrophilic and partially hydrophobic, interposed across the path of the liquid and the air, at the base of the said nozzle. In the dispensing head, the proposal is to create the nozzle by itself out of a material containing a bactericidal agent that has the effect of preventing any bacterial growth on the surface of the said nozzle on the outside of the antibacterial membrane. A porous core is advantageously positioned inside the duct through which liquid is expelled and air is admitted.Type: ApplicationFiled: July 31, 2009Publication date: May 26, 2011Applicant: LABORATORIES THEAInventors: Jean-Frédéric Chibret, Alain Defemme, Michel Faurie, Fabrice Mercier
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Patent number: 7064109Abstract: The invention relates to a pharmaceutical composition for preventing and/or treating eye infections, which is to be used by local application. It is in particular directed towards such a composition which is in the form of an eye lotion which can be distributed by drops, in which an antibiotic of the macrolide class, such as azithromycin, is in solution in an oily vehicle. This vehicle is, in particular, of the type of product essentially consisting of medium-chain triglycerides in which the alcohol functions of the glycerol are entirely esterified by carboxylic acids made from saturated hydrocarbons, the molecule of which comprises from 5 to 12 carbon atoms. They are preferably linear-chain fatty acids comprising from 8 to 10 carbon atoms, such as caprylic acid or capric acid. The composition is advantageously prepared by dissolving the active agent in the oily vehicle at a temperature not exceeding 70° C.Type: GrantFiled: April 11, 2002Date of Patent: June 20, 2006Assignee: Laboratories TheaInventors: Jacques Luyckx, Frederic Pilotaz