Patents Assigned to Laboratorio Italiano Biochimico Farmaceutico Lisapharma S.p.A.
  • Patent number: 6773722
    Abstract: Sucralfate gel in the dry state in porous granular form having a particle-size distribution of between 100 and 1000 &mgr;m, an apparent density of the powder bed of between 0.7 and 0.9 g/ml, a settling index of between 5 and 15%, and a residual humidity of between 5 and 15%, and the corresponding process of preparation, which comprises a treatment with microwaves of a diluted solution of powdered sucralfate gel, with a sucralfate titer of between 20 and 70 wt. %. This solid product may be advantageously used in the preparation of solid pharmaceutical compositions that contain it as single active principle, or else as coating of solid compositions that contain, as active principle, a substance that may cause lesions to the gastric mucosa.
    Type: Grant
    Filed: May 29, 2003
    Date of Patent: August 10, 2004
    Assignee: Laboratorio Italiano Biochimico Farmaceutico Lisapharma S.p.A.
    Inventors: Giorgio Zagnoli, Paolo Colombo, Loretta Maggi, Fabrizio Cudazzo
  • Patent number: 6706286
    Abstract: Sucralfate gel in the dry state in porous granular form having a particle-size distribution of between 100 and 1000 &mgr;m, an apparent density of the powder bed of between 0.7 and 0.9 g/ml, a settling index of between 5 and 15%, and a residual humidity of between 5 and 15%, and the corresponding process of preparation, which comprises a treatment with microwaves of a diluted solution of powdered sucralfate gel, with a sucralfate titre of between 20 and 70 wt. %. This solid product may be advantageously used in the preparation of solid pharmaceutical compositions that contain it as single active principle, or else as coating of solid compositions that contain, as active principle, a substance that may cause lesions to the gastric mucosa.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: March 16, 2004
    Assignee: Laboratorio Italiano Biochimico Farmaceutico Lisapharma S.p.A.
    Inventors: Giorgio Zagnoli, Paolo Colombo, Loretta Maggi, Fabrizio Cudazzo
  • Patent number: 5661137
    Abstract: Antiacid pharmaceutical compositions in the form of suspensions containing sucralphate gel as an active ingredient combined with suitable excipients and/or diluents.
    Type: Grant
    Filed: January 29, 1996
    Date of Patent: August 26, 1997
    Assignee: Laboratorio Italiano Biochimico Farmaceutico Lisapharma S.p.A.
    Inventor: Giorgio Zagnoli
  • Patent number: 5246697
    Abstract: The use of sucralfate humid gel is described as vehicle for the application f drugs having topic activity (dermic and mucosal) and as basis for the formulation of beauty masks and other cosmetic preparations. Therapeutic and cosmetic formulations are described in the form of creams, ointments, aqueous dispersions comprising sucralfate humid gel.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: September 21, 1993
    Assignee: Laboratorio Italiano Biochimico Farmaceutico Lisapharma S.p.A.
    Inventors: Ubaldo Conte, Paolo Colombo, Giorgio Zagnoli, Carla Caramella