Abstract: The invention relates to a device for adjusting the temperature of a physiological fluid. The inventive device includes: a casing (1), a first heat energy generating unit (2), a heat energy receiving unit (3) through which the fluid flows along a passage from a fluid inlet (3a) to a fluid outlet (3b) and which consists of a flat body (3d) having a first large surface (3e) which is made from a heat conductor material, and a control unit (4) for controlling at least the first generating unit (2). According to the invention, the first generating unit (2) includes first units of Peltier cells (5) and at least one first contact plate (6) which is made from a heat conductor material and which is placed in contact with a first side (5b, 8b) of the units of Peltier cells (5). In addition, the receiving unit (3) is removably installed in the first generating unit (2) such that it is in contact with the first contact plate (6).