Patents Assigned to Laboratorios Dalmer SA
  • Patent number: 6486205
    Abstract: A new natural mixture of primary fatty acids of high molecular weight ranging from 24 to 38 carbon atoms, especially those ranging between 26 and 36 carbon atoms and more especially those of straight chain of 26, 28, 29, 30, 31, 32, 33, 34, 35 and 36 carbon atoms. This mixture has a relative composition of each fatty acid that is highly reproducible batch to batch and it is extracted from sugar cane (Saccharum officinarum, L.) wax. This mixture of fatty acids has specific pharmacological properties that supports its use as an active component of pharmaceutical formulations used as hypocholesterolemic and against hypercholesterolaemia type II, as antiplatelet, anti-thrombotic and anti-ischemic. This mixture of primary fatty acids is also effective in the inhibition of the development of gastric ulcers induced by different agents.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: November 26, 2002
    Assignee: Laboratorios Dalmer SA
    Inventors: Luis Gonzáles Bravo, David Marrero Delange, Abilo Laguna Granja, Rosa Maria Más Ferreiro, Maria de Lourdes Arruzazabala Valmana, Daysi Carbajal Quintana, Mirian Cora Medina, Roberto Menendez Soto del Valle
  • Patent number: 6235795
    Abstract: This invention is related with the obtention of a new natural mixture composed by higher primary aliphatic alcohols, eventually in an extended range of 22 to 38 carbon atoms, specially those between 24 and 34 carbon atoms and more specially those of 24, 26, 28, 30, 32 and 34 carbon atoms. This mixture shows a relative composition of each alcohol that is highly reproducible from batch to batch and is obtained from bee wax. This natural mixture has been used, with efficacy, as an active principle, in different pharmaceutical formulations used against ulcer, and/or protector of the gastric and duodenal mucose, and shows antiinflamatory activity administered by topical, oral or parenteral route.
    Type: Grant
    Filed: November 7, 1994
    Date of Patent: May 22, 2001
    Assignee: Laboratorios Dalmer SA
    Inventors: Juan Magraner Hernandez, Abilio Laguna Granja, Rosa Mas Ferreiro, Maria de Lourdes Arruzazabala Valmaña, Daysi Carvajal Quintana, Vivian Molina Sánchez, Suria Valdés García, Maritza Díaz Gómez
  • Patent number: 5856316
    Abstract: A mixture of higher primary aliphatic alcohols of 22 to 38 carbon atoms can be obtained by saponifying and extracting steps with organic solvents from sugar cane wax. The mixture which contains tetracosanol, hexacosanol, heptacosanol, octacosanol, nonacosanol, triacontanol, dotriacontanol and tetratriacontanol can be used for the treatment of hypercholesterolemia, and atherosclerotic complications as platelet hyperaggregabiulity, ischemia and thrombosis, and prevents drug induced gastric ulcer and improves male sexual activity.
    Type: Grant
    Filed: December 23, 1996
    Date of Patent: January 5, 1999
    Assignee: Laboratorios Dalmer SA
    Inventors: Abilio Laguna Granja, Juan Magraner Hernandez, Daisy Carbajal Quintana, Lourdes Arruzazabala Valmana, Rosa Mas Ferreiro, Milagros Garcia Mesa
  • Patent number: 5663156
    Abstract: A mixture of higher primary aliphatic alcohols of 22 to 38 carbon atoms can be obtained by saponifying and extracting steps with organic solvents from sugar cane wax. The mixture which contains tetracosanol, hexacosanol, heptacosanol, octacosanol, nonacosanol, triacontanol, dotriacontanol and tetratriacontanol can be used for the treatment of hypercholesterolemia, and atherosclerotic complications as platelet hyperaggregabiulity, ischemia and thrombosis, and prevents drug induced gastric ulcer and improves male sexual activity.
    Type: Grant
    Filed: July 25, 1994
    Date of Patent: September 2, 1997
    Assignees: Laboratorios Dalmer SA, Adanifer, S.A.
    Inventors: Abilio Laguna Granja, Juan Magraner Hernandez, Daisy Carbajal Quintana, Lourdes Arruzazabala Valmana, Rosa Mas Ferreiro, Milagros Garcia Mesa