Abstract: The pharmaceutical formulation consists of a number of pellets that comprise an inert nucleus, a layer with the active ingredient, one or more intermediate layers that comprise at least a system of modified release, and an external layer of enteric coating. These pellets can be obtained applying the different layers by means of fluid bed coating techniques using aqueous solutions or suspensions of the components of such layers. The pharmaceutical formulations can be hard gelatin capsules or tablets and are suitable for use in the prevention and treatment of disorders related to abnormal gastric acid secretion.
Type:
Grant
Filed:
September 12, 2000
Date of Patent:
August 24, 2004
Assignee:
Laboratorios Del Dr. Esteve, SA
Inventors:
Antonio López-Cabrera, Pedro Juan Solanas-Ibarra, Vincent Mancinelli
Abstract: Salts of p-dihydroxy benzene disulfonic acids having the general formula: ##SPC1##Wherein B is an alkali metal or an equivalent of an alkaline-earth metal, or BH is the cation of ammonia or a nitrogen containing basic organic compound, are useful for reducing the average bleeding time and for combating capillary fragility.
Abstract: A process for preparing a bean odor-free soy bean product which comprises subjecting a soy milk to lactic fermentation in the presence of a lactic acid bacterium as a starter and subjecting the resultant fermented soy milk to distillation under reduced pressure, the soy bean product being suitable for the manufacture of a nutritional drink or beverage product free from a bean odor due to its high protein concentration and excellent palatability.