Patents Assigned to Labortoire Francais du Fractionnement et des Biotechnologies
  • Monoclonal antibodies with enhanced ADCC function
    Patent number: 8685725
    Abstract: The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADDC-type test, said antibodies capable of activating type III Fcy receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunization in Rh negative persons, in particular for haemolytic disease in a new-born baby of for uses such as idiopathic thrombocytopenic pupura 9ITP.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: April 1, 2014
    Assignee: Labortoire Francais du Fractionnement et des Biotechnologies
    Inventors: Roland Beliard, Dominique Bourel, Arnaud Glacet, Christophe De Romeuf, Nicolas Bihoreau, Emmanuel Nony