Patents Assigned to LABTEC GMBH
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Publication number: 20230181486Abstract: The present invention relates to a method of diagnosis of primary headache. More particular, the invention relates to a method of differentiating between primary and secondary headache in a human subject by applying a biomarker for primary headache. In a particular aspect, the invention relates to a method for the diagnosis of migraine. In one particular aspect the invention relates to the field of theranostic and personalized medicine.Type: ApplicationFiled: May 19, 2021Publication date: June 15, 2023Applicant: TESA LABTEC GMBHInventors: Helge LUBENOW, Svenja NIESE, Steffen ERNST
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Publication number: 20230172848Abstract: The present invention relates to dosage units of oral films for the administration of active pharmaceutical ingredients (API), such as analgesics, relaxants, anxiolytics, sedatives, hypnotics, narcotics, anesthetics and/or other API with peripheral and/or central nervous effects, in particular for use in the treatment of pain, metabolic disorders and diseases of the central nervous system (CNS). More particular the invention relates to dosage units of oral films comprising relaxants, anxiolytics, sedatives, hypnotics, narcotics, anesthetics and/or analgesics prone to misuse and abuse, such as overdosing. More particular, the invention relates to dosage units of oral films comprising propofol. In a further aspect, the invention relates to dosage units of oral films comprising propofol for use in the treatment of a subject suffering from migraine.Type: ApplicationFiled: May 19, 2021Publication date: June 8, 2023Applicant: LABTEC GMBHInventors: Helge LUBENOW, Svenja NIESE, Sebastian BRAUN, Steffen ERNST, Eva Saskia Mareike LUTZ
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Patent number: 9539206Abstract: Method for producing and monitoring oral active ingredient films with a base to which a solution containing at least one active ingredient is applied, the method comprising the steps: • metering and mixing the base formulation, • coating the base formulation onto a substrate, so that a strip results • if necessary, drying the base formulation strip coated on the substrate • printing a colorant solution containing at least one active ingredient onto the upper side of the base formulation strip according to the flexographic printing method, • drying the base formulation strip coated on the substrate together with the printed active ingredient solution, • penetrating the base formulation strip coated on the substrate together with the printed active ingredient solution from the upper and/or lower side by means of radiation from a radiation source, • measuring the transmission of the penetrating radiation by means of at least one reception unit on the opposite side of the base formulation strip coated on the subsType: GrantFiled: July 9, 2012Date of Patent: January 10, 2017Assignees: TESA SE, TESA LABTEC GMBHInventors: Sebastian Braun, Armin Breitenbach, Ralf Schliephacke
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Publication number: 20160158161Abstract: A process for producing an adhesive matrix for a transdermal therapeutic system comprising a cover layer, the adhesive matrix, and a removable protective layer. The process includes providing a solution comprising polybutyl titanate dissolved in heptane:ethyl alcohol, providing an acrylate copolymer consisting of units of 2-ethylhexyl acrylate, methacrylate and 2-hydroxyethyl acrylate, adding the solution to the acrylate copolymer to obtain a mixture, and adding fentanyl as an active ingredient to the mixture to obtain the adhesive matrix.Type: ApplicationFiled: February 17, 2016Publication date: June 9, 2016Applicant: TESA LABTEC GMBHInventors: Guenter CORDES, Ulrike VOLLMER
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Patent number: 9320721Abstract: A mucoadhesive patch that consists of an adhesive layer and a backing layer, wherein the adhesive layer contains a nonionic and an anionic hydrocolloid in a weight ratio of 1:2 to 1:5, and the backing layer contains a matrix of a nonionic and an anionic hydrocolloid in a weight ratio of 2:1 to 5:1.Type: GrantFiled: September 1, 2005Date of Patent: April 26, 2016Assignee: TESA LABTEC GMBHInventor: Ulrike Vollmer
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Publication number: 20140272099Abstract: Method for producing and monitoring oral active ingredient films with a base to which a solution containing at least one active ingredient is applied, the method comprising the steps: • metering and mixing the base formulation, • coating the base formulation onto a substrate, so that a strip results • if necessary, drying the base formulation strip coated on the substrate • printing a colorant solution containing at least one active ingredient onto the upper side of the base formulation strip according to the flexographic printing method, • drying the base formulation strip coated on the substrate together with the printed active ingredient solution, • penetrating the base formulation strip coated on the substrate together with the printed active ingredient solution from the upper and/or lower side by means of radiation from a radiation source, • measuring the transmission of the penetrating radiation by means of at least one reception unit on the opposite side of the base formulation strip coated on the subsType: ApplicationFiled: July 9, 2012Publication date: September 18, 2014Applicants: Tesa Labtec GmbH, Tesa SEInventors: Sebastian Braun, Armin Breitenbach, Ralf Schliephacke
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Publication number: 20140186427Abstract: The present invention pertains to oral applicable therapeutic dosage forms, in particular to orodispersible films. The present invention especially is directed to orodispersible films comprising a base layer substantially free of therapeutically active agents and a top layer comprising the desired therapeutically active agents. The present invention also concerns suitable base layers for such orodispersible films as well as therapeutical uses thereof and methods for manufacturing them.Type: ApplicationFiled: August 13, 2012Publication date: July 3, 2014Applicant: TESA LABTEC GMBHInventors: Armin Breitenbach, Sebastian Braun, Ralf Schliephacke
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Publication number: 20140170208Abstract: A method for preparing a transdermal patch comprising a substrate layer is provided, the method comprising the steps of contacting an active pharmaceutical ingredient with a retaining means to provide a composition, applying the composition obtained in step (a) to a carrier material to form a substrate layer of the transdermal patch, wherein the retaining means remain within the final transdermal patch.Type: ApplicationFiled: February 21, 2014Publication date: June 19, 2014Applicant: LABTEC GMBHInventors: Sebastian BRAUN, Armin BREITENBACH, Ulrich BECKER
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Patent number: 8580830Abstract: Orally disintegrating film dosage forms for delivering active pharmaceutical agents, methods of formulating the dosage forms to retard absorption through the oral mucosa, and methods of using the dosage forms for the treatment of various medical conditions are provided.Type: GrantFiled: October 2, 2007Date of Patent: November 12, 2013Assignees: Labtec GmbH, APR Applied Pharma Research S.A.Inventors: Christian Leichs, Armin Breitenbach, Ingo Lehrke, Paolo Galfetti
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Publication number: 20120265158Abstract: A method for preparing a transdermal patch comprising a substrate layer is provided, the method comprising the steps of contacting an active pharmaceutical ingredient with a retaining means to provide a composition, applying the composition obtained in step (a) to a carrier material to form a substrate layer of the transdermal patch, wherein the retaining means remain within the final transdermal patch.Type: ApplicationFiled: September 9, 2010Publication date: October 18, 2012Applicant: LABTEC GMBHInventors: Sebastian Braun, Armin Breitenbach, Ulrich Becker
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Publication number: 20090130190Abstract: Methods and systems for the transdermal delivery of sufentanil and its analogs are described, from patches having a unique pharmacodynamic profile that can be used to treat persistent pain over extended periods and acute pain episodes of limited duration.Type: ApplicationFiled: October 21, 2008Publication date: May 21, 2009Applicant: LABTEC GMBHInventors: Armin Breitenbach, Peter Klaffenbach, Ingo Lehrke, Ulrike Vollmer