Patents Assigned to Lahive and Cockfield, LLP
  • SENSE MRNA THERAPY
    Publication number: 20030083272
    Abstract: The present invention describes novel methods for the stabilization of mRNA. These alterations increase stability of mRNA and enable its use in sense RNA therapy to transiantly express proteins in a cell. Accordingly, the present invention is directed to methods for making such modifications, compositions comprising such modifications, and the use of such compositions in treating disease states.
    Type: Application
    Filed: September 18, 1998
    Publication date: May 1, 2003
    Applicant: LAHIVE & COCKFIELD, LLP
    Inventors: KRISTIN WIEDERHOLT, Tod M. Woolf, Margaret Taylor
  • Phosphono-carboxylate compounds for treating amyloidosis
    Publication number: 20030027796
    Abstract: Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.
    Type: Application
    Filed: August 23, 2002
    Publication date: February 6, 2003
    Applicant: Lahive & Cockfield, LLP
    Inventors: Walter A. Szarek, Xianqi Kong, Gregory R.J. Thatcher, Boris Gorine
  • Intravenous valproate for acute treatment of migraine headache
    Publication number: 20020156131
    Abstract: The present invention features a novel therapy for effecting acute treatment of migraine headache. The therapy involves intravenous administration of valproate and is equal to and in some respects superior to previously-known therapies for abortive treatment of prolonged moderate to severe acute migraine headache.
    Type: Application
    Filed: December 27, 2001
    Publication date: October 24, 2002
    Applicant: LAHIVE & COCKFIELD, LLP.
    Inventor: Keith R. Edwards
  • Fluid-recovery system with integrally molded components
    Publication number: 20020055690
    Abstract: The present invention relates to fluid recovery systems for collecting fluid from a patient. A fluid recovery system according to the teachings of the invention includes a housing having a collection chamber for collecting fluid from a patient, and further includes a plurality of components and/or structures that are integrally formed with the housing. Such integrally molded components can include valves for controlling fluid flow within the fluid recovery system and a tamper resistant disposal system.
    Type: Application
    Filed: January 4, 2002
    Publication date: May 9, 2002
    Applicant: Lahive and Cockfield, LLP
    Inventors: Nicholas Want, Theodore Karwoski, Steve A. Herweck, Thomas S. Cochran, Scott E. Corbeil, David R. Autote, Ralph L. Gillis