Patents Assigned to LanzaTech New Zealand Limited
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Patent number: 8809015Abstract: Methods and systems for the production of hydrocarbon products, including providing a substrate comprising CO to a bioreactor containing a culture of one or more micro-organisms; and fermenting the culture in the bioreactor to produce one or more hydrocarbon products. The substrate comprising CO is derived from an industrial process selected from the group comprising steam reforming processes, refinery processes, steam cracking processes, and reverse water gas shift processes.Type: GrantFiled: October 21, 2011Date of Patent: August 19, 2014Assignee: LanzaTech New Zealand LimitedInventors: Michael Anthony Schultz, James Obern, Sean Dennis Simpson
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Publication number: 20140212937Abstract: The invention provides a microbubble generation system with increased efficiency and flexibility compared to known systems. Further, the invention provides a method of microbubble generation. In particular, invention relates to increasing the efficiency of a fermentation reaction by reducing bubble size and increasing gas absorption into a liquid fermentation broth.Type: ApplicationFiled: January 28, 2014Publication date: July 31, 2014Applicant: LanzaTech New Zealand LimitedInventor: Xueliang Li
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Publication number: 20140212976Abstract: The invention provides a recombinant carboxydotrophic Clostridia microorganism with increased overall utilization of NADPH relative to a parent microorganism. Further, the invention provides a method of producing a recombinant carboxydotrophic Clostridia microorganism which exhibits increased NADPH utilization relative to a parental microorganism. In particular, the invention relates to increasing the overall utilization of NADPH in a recombinant carboxydotrophic Clostridia microorganism in order to increase the production of at least one fermentation product by the microorganism.Type: ApplicationFiled: January 30, 2014Publication date: July 31, 2014Applicant: LanzaTech New Zealand LimitedInventors: Alexander Paul Mueller, Michael Koepke
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Publication number: 20140186928Abstract: The invention relates, inter alia, to novel genetically modified microorganisms capable of using CO to produce 1-butanol and/or a precursor thereof, novel methyltransferases and nucleic acids encoding same, methods for producing genetically modified microorganisms using said novel methyltransferases, and methods of producing 1-butanol and/or a precursor thereof by microbial fermentation.Type: ApplicationFiled: February 14, 2014Publication date: July 3, 2014Applicant: LANZATECH NEW ZEALAND LIMITEDInventors: Michael Koepke, Sean Dennis Simpson, FungMin Liew
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Publication number: 20140154755Abstract: The invention provides methods and systems for the production of lipid products from a gaseous substrate using a two stage fermentation process. The method comprises providing a gaseous substrate comprising CO or CO2 and H2 or mixtures thereof, to a first bioreactor containing a culture or one or more microorganisms, and fermenting the substrate to produce acetate. The acetate from the first bioreactor is then provided to a second bioreactor, where it is used as a substrate for fermentation to lipids by one or more microalgae.Type: ApplicationFiled: November 29, 2013Publication date: June 5, 2014Applicant: LanzaTech New Zealand LimitedInventors: Sean Dennis Simpson, Sebastian Michal Bernasek
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Patent number: 8735115Abstract: This invention relates generally to methods for increasing the efficiency of microbial growth and production of products, such as alcohols and acids by microbial fermentation of substrates containing carbon monoxide. More particularly the invention relates to the provision of an alternative sulphur source to a liquid nutrient medium, such that sulphur is available to one or more microorganisms of the fermentation.Type: GrantFiled: March 27, 2013Date of Patent: May 27, 2014Assignee: LanzaTech New Zealand LimitedInventors: Christophe Daniel Mihalcea, Prana Haryanto, Sean Dennis Simpson
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Publication number: 20140141477Abstract: The invention provides methods and systems for the production of lipid products from a gaseous substrate using a two stage fermentation process. The method comprises providing a gaseous substrate comprising CO, CO2 and H2 or mixtures thereof, to a first bioreactor containing a culture or one or more microorganisms, and fermenting the substrate to produce a product comprising acetate. The acetate from the first bioreactor is then provided to a second bioreactor, where it is used as a substrate for fermentation to lipids by one or more yeasts.Type: ApplicationFiled: November 15, 2013Publication date: May 22, 2014Applicant: LanzaTech New Zealand LimitedInventors: Sean Dennis Simpson, Sebastian Michal Bernasek
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Patent number: 8673603Abstract: Methods for improving the efficiency of 2,3-butanediol fermentations are disclosed. More specifically methods of increasing the butanediol productivity from the anaerobic fermentation of a substrate comprising carbon monoxide or carbon monoxide and hydrogen by one or more caboxydotrophic acetogenic bacteria are disclosed. The method includes supplying a hydrogen depleted substrate to increase butanediol productivity. The method includes producing butanediol at a volumetric productivity rate of at least 15 g/L/day.Type: GrantFiled: March 30, 2012Date of Patent: March 18, 2014Assignee: LanzaTech New Zealand LimitedInventors: Sean Dennis Simpson, Christophe Collet, Christophe Daniel Mihalcea, Joshua Jeremy Conolly, Guy William Waters
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Publication number: 20140065698Abstract: A stereospecific enzyme in C. autoethanogenum permits the conversion of racemic propanediol to acetone and/or propionaldehyde. Entantiomeric starting materials lead to different products. If desired, the products may be reduced to form alcohols. The reaction can be performed in various host cells, so that various materials may be used as carbon and/or energy sources.Type: ApplicationFiled: August 28, 2013Publication date: March 6, 2014Applicant: LanzaTech New Zealand LimitedInventors: Alexander Paul Mueller, Michael Koepke
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Patent number: 8663949Abstract: This invention relates to the integration of an ammonia production process with a fermentation process to produce products such as alcohols and/or acids in addition to ammonia. In a specific embodiment, a natural gas stream comprising methane is passed to a reforming zone to produce a substrate comprising CO and H2. The substrate is next passed to a bioreactor containing a culture of one or more microorganisms and fermenting the culture to produce one or more fermentation products comprising alcohols and/or acids and an exhaust stream comprising CO2, and H2. The exhaust stream can then be passed to a separation zone to remove at least a portion of the CO2 and produce a purified exhaust stream comprising H2 which is then passed to an ammonia production zone and is used to produce ammonia.Type: GrantFiled: December 19, 2011Date of Patent: March 4, 2014Assignee: LanzaTech New Zealand LimitedInventor: Michael Anthony Schultz
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Patent number: 8658402Abstract: Methods for producing an ester from a gas comprising carbon monoxide. More specifically the invention provides for methods for producing one or more products by the anaerobic fermentation of a gaseous substrate comprising CO and the subsequent conversion of the one or more products to an ester in a down-stream reaction. The invention further provides methods for improving the efficiency of the production of esters from gaseous substrates.Type: GrantFiled: May 22, 2012Date of Patent: February 25, 2014Assignee: LanzaTech New Zealand LimitedInventors: Michael Anthony Schultz, Derek Wayne Griffin
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Publication number: 20130330809Abstract: Carboxydotrophic acetogenic microorganisms do not produce MEK and/or 2-butanol. They lack the biosynthesis pathways to make these products. In addition, they produce the intermediate (R,R)-2,3-butanediol whereas the production of MEK and 2-butanol requires production of the intermediate (R,S)-2,3-butanediol. Nonetheless, the production of MEK and/or 2-butanol can be accomplished using recombinant microorganisms adapted to express or overexpress key enzymes in the MEK and/or 2-butanol biosynthesis pathways. Such microorganisms, such as the carboxydotrophic acetogen Clostridium autoethanogenum, can ferment substrates comprising CO. The overall scheme involves the production of 2-butanol from (R,S)-2,3-butanediol and the conversion of (R)-acetoin to (S)-2,3-butanediol. These steps are involved in the production of both MEK and 2-butanol. Such fermentation methods offer a means of using carbon monoxide from industrial processes which would otherwise be released into the atmosphere and pollute the environment.Type: ApplicationFiled: June 10, 2013Publication date: December 12, 2013Applicant: LanzaTech New Zealand LimitedInventors: Alexander Paul Mueller, Michael Koepke, Shilpa Nagaraju
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Publication number: 20130323806Abstract: Bacteria are genetically engineered to produce 3-hydroxypropionate (3-HP). The bacteria are carboxydotrophic acetogens. The bacteria produce acetyl-coA using the Wood-Ljungdahl pathway for fixing CO/CO2. A malonyl-coA reductase from a bacterium that contains such an enzyme is introduced. Additionally, an acetyl-coA carboxylase may also be introduced The production of 3-HP can be improved by overproduction of acetyl-CoA carboxylase or by overproduction of biotin. This can be effected by improved promoters or higher copy number or enzymes that are catalytically more efficient.Type: ApplicationFiled: May 30, 2013Publication date: December 5, 2013Applicant: LanzaTech New Zealand LimitedInventors: Michael Koepke, Wendy Yiting Chen
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Publication number: 20130323820Abstract: Terpenes are valuable commercial products used in a diverse number of industries. Terpenes may be produced from petrochemical sources and from terpene feed-stocks, such as turpentine. However, these production methods are expensive, unsustainable and often cause environmental problems including contributing to climate change. Microbial fermentation provides an alternative option for the production of terpenes. One or more terpenes and/or precursors can be produced by microbial fermentation of a substrate comprising CO. Recombinant microorganisms may be used in such methods. Carboxydotrophic, acetogenic, recombinant microorganisms can be used in such methods. The recombinant microorgnsims may contain exogenous mevalonate (MVA) pathway enzymes and/or DXS pathway enzymes, for example.Type: ApplicationFiled: June 3, 2013Publication date: December 5, 2013Applicant: LanzaTech New Zealand LimitedInventors: Wendy Yiting Chen, FungMin Liew, Michael Koepke
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Publication number: 20130316412Abstract: The invention provides an improved method for the production, separation and recovery of one or more fermentation products from a fermentation broth. Further, the invention provides a method for increasing efficiency of a fermentation reaction.Type: ApplicationFiled: May 23, 2013Publication date: November 28, 2013Applicant: LanzaTech New Zealand LimitedInventors: Michael Anthony Schultz, Alice Marie Havill, Anil R. Oroskar
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Publication number: 20130316424Abstract: The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas.Type: ApplicationFiled: July 28, 2013Publication date: November 28, 2013Applicant: LanzaTech New Zealand LimitedInventors: Sean Dennis Simpson, Christophe Collet, Michael Cockrem, Simon David Oakley, Michael Koepke
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Publication number: 20130316364Abstract: One or more genes in a biosynthesis pathway for a vitamin or other essential nutrient which is needed for the survival of a microorganism can be used as an effective selective marker to identify cells transformed with an exogenous nucleic acid. The microorganism does not naturally contain or express the one or more gene. This permits genetic manipulations to be performed. It permits lower cost fermentations to be performed. It permits production of the essential nutrient for subsequent commodity use.Type: ApplicationFiled: May 22, 2013Publication date: November 28, 2013Applicant: LanzaTech New Zealand LimitedInventor: LanzaTech New Zealand Limited
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Publication number: 20130267006Abstract: The present invention relates to mutant alcohol dehydrogenase enzymes, microorganisms comprising same, and methods for the production of one or more products by microbial fermentation using said microorganisms.Type: ApplicationFiled: April 5, 2013Publication date: October 10, 2013Applicant: LANZATECH NEW ZEALAND LIMITEDInventors: Michael Koepke, Wayne Michael Patrick, Danielle Joan Maddock, Monica Gerth
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Publication number: 20130260429Abstract: This invention relates generally to methods for increasing the efficiency of microbial growth and production of products, such as alcohols and acids by microbial fermentation of substrates containing carbon monoxide. More particularly the invention relates to the provision of an alternative sulphur source to a liquid nutrient medium, such that sulphur is available to one or more microorganisms of the fermentation.Type: ApplicationFiled: March 27, 2013Publication date: October 3, 2013Applicant: LanzaTech New Zealand LimitedInventors: Christophe Daniel Mihalcea, Prana Haryanto, Sean Dennis Simpson
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Publication number: 20130252230Abstract: The invention relates to a process for optimising the production of ethanol by microbial fermentation, particularly microbial fermentation of substrates comprising CO. The process involves monitoring the hydrogen production by the microorganism, determining an optimum hydrogen production and adjusting the substrate supply rate in response to a change in the hydrogen production thereby keeping the hydrogen production within a desired range.Type: ApplicationFiled: April 29, 2013Publication date: September 26, 2013Applicant: LanzaTech New Zealand LimitedInventors: Will David Barker, Bjorn Daniel Heijstra, Wing Chuen Chan, Christophe Daniel Mihalcea, Loan Phuong Tran, Christophe Collet, Jason Carl Bromley, Bakir Al-Sinawi