Abstract: A boron-nitrogen ligand with a chiral 1,2-ethylenediamine backbone, a preparing method and used thereof are provided. The structural formula of the boron-nitrogen ligand is as shown in formula (I): wherein R1, R2 and R3 are respectively at least independently selected from substituted or unsubstituted C3-C10 cycloalkyl, C1-C10 alkyl or aryl; R4, R5, R6, R7, R8, R9, R10, R11 and R12 are respectively at least independently selected from hydrogen, halogen, substituted or unsubstituted C1-C10 alkyl, C1-C4 alkoxy, C3-C30 cycloalkyl or aryl; Ar1 and Ar2 are respectively at least independently selected from substituted or unsubstituted C6-C30 aryl. The preparation method of the present application is simple, and can be used for preparing a racemic or chiral boron-nitrogen ligand, which can be used as a catalyst for an asymmetric catalytic reaction and has economic practicability and industrial application prospects.

Abstract: The present invention discloses a phthalide derivative, the structure of said derivative is represented by Formula (I) or Formula (II). The present invention also discloses the preparation method and use of said derivative. The phthalide compound obtained through structure modifications in the present invention enhances the chemical stability and pharmacological activity of the phthalide compound, facilitating the improvement of the druggability of such compounds.

Abstract: A boron-nitrogen ligand with a chiral 1,2-ethylenediamine backbone, a preparing method and used thereof are provided. The structural formula of the boron-nitrogen ligand is as shown in formula (I): wherein R1, R2 and R3 are respectively at least independently selected from substituted or unsubstituted C3-C10 cycloalkyl, C1-C10 alkyl or aryl; R4, R5, R6, R7, R8, R9, R10, R11 and R12 are respectively at least independently selected from hydrogen, halogen, substituted or unsubstituted C1-C10 alkyl, C1-C4 alkoxy, C3-C30 cycloalkyl or aryl; Ar1 and Ar2 are respectively at least independently selected from substituted or unsubstituted C6-C30 aryl. The preparation method of the present application is simple, and can be used for preparing a racemic or chiral boron-nitrogen ligand, which can be used as a catalyst for an asymmetric catalytic reaction and has economic practicability and industrial application prospects.

Abstract: The present invention relates to the field of 3D printing technology, and provides a photocurable 3D printing polyimide ink, and a preparation method and application thereof. The photocurable 3D printing polyimide ink includes the following components in the following weight percentages: 40 to 60% of a photocurable polyamic acid, 5 to 40% of an organic solvent, 10 to 50% of a reactive diluent, 1 to 10% of a chain extender, and 1 to 3% of a photoinitiator. The photocurable 3D printing polyimide ink provided by the present invention has excellent mechanical properties, thermal stability, relatively high printing accuracy and relatively low shrinkage; a molded device obtained by 3D printing has excellent properties including high accuracy, great dimensional stability, high strength and corrosion resistance, excellent flexibility, high temperature resistance and relatively low shrinkage. The method for preparing the photocurable 3D printing polyimide ink has a simple process and lower energy consumption.

Abstract: A method for preparing a direct-writing polyimide additive manufacturing (AM) material includes (1) conducting ultraviolet curing immediately after the photosensitive polyimide ink is subjected to direct-writing extrusion, to obtain a polyimide precursor formed member; and (2) heat-treating the polyimide precursor formed member obtained in step (1) to obtain the direct-writing polyimide AM material. The direct-writing polyimide AM material obtained by using the method of the present invention has excellent comprehensive properties.

Abstract: The present invention provides a waterborne self-polishing antifouling paint and a preparation method and application thereof, and belongs to the technical field of marine antifouling paints. The waterborne self-polishing antifouling paint provided by the present invention includes the following components in parts by weight: 30-60 parts of waterborne self-polishing emulsion, 30-70 parts of waterborne slurry, 0.1-0.5 parts of waterborne leveling agent, 0.2-1 parts of waterborne defoamer, 0.5-1 parts of film-forming additive and 10-20 parts of water. The waterborne self-polishing antifouling paint provided by the present invention has an ultra-low content of volatile organic compounds (VOCs) (less than 20 g/L), and is environmentally friendly. The waterborne self-polishing antifouling paint can be formed into a paint film with good mechanical properties, stable self-polishing rate, and excellent water immersion resistance and antifouling performance.

Abstract: Provided is a process for the production of an aromatic compound comprising at least two amine functions, comprising reacting an aromatic compound having at least one hydroxyl function and at least one aldehyde function with a second reactant having an amine function, in the presence of a reductant agent and a catalyst comprising at least one metal element in elemental form and/or at least one metal oxide.

Abstract: A derivative of isocorydine of formula I: wherein: R1? X?N, C, C?C; n1=0, 1 R2?H, R1 Y?C, N R3?H, Cl, Br, F, CF3, OCH3, CH3, Z ?H, Cl, F, N; n2=0, 1 R4?NH2, CH2NH2, NHCO(CH2)n3CH3, CH2NHCO(CH2)n3CH3, n3=0, 1, 2. This derivative is prepared by amidation condensation reaction between an amino group of NICD and a carbonyl group of an aryl isocyanate, a carboxylic acid, or an acid chloride, or symmetrical amidation condensation reaction between an NICD and an aromatic amino group by solid phosgene. This derivative has anti-cancer activity in vivo and in vitro, and may be used for preventing and treating cancer.

Abstract: The present invention discloses a method for preparing a double-network hydrogel tube with a complex structure. Iron wires of different sizes are mechanically polished, arranged in different manners, and then immersed into a monomer prepolymer solution, or a monomer prepolymer is poured into a container containing iron wires of different arranged shapes to conduct a polymerization reaction, such that a uniform primary-crosslinked single-network hydrogel film can be rapidly grown on the surface of each iron wire. The hydrogel film is then immersed in a secondary-crosslinking solution for secondary crosslinking to build a double-network hydrogel film. After immersion processing, the wires are drawn out to obtain high-strength hollow double-network hydrogel tubes of different shapes. The hydrogel tube has a diameter of 10 micrometers to a few millimeters, the shape of the tube inner structure is highly controllable, and the tensile strength of the hydrogel tube can be up to 2 MPa.

Abstract: A system and method for producing polyoxymethylene dimethyl ethers (DMMn) using an aqueous formaldehyde solution as the initial reaction material. The process system has a polymerization reaction unit, an acetalation unit, a product separation unit, and a catalyst regeneration unit. Both polymerization and acetalation reaction are conducted in the presence of an ionic liquid as a catalyst, which can achieve the effect that two different reactions may be catalyzed by the same ionic liquid. The present invention employs a simple catalyst system, and achieves the efficient separation of the catalyst, the byproduct water, the product and the reaction materials in a separation manner combining the extraction and the rectification.

Abstract: The invention relates to a reaction system and process for continuously preparing polymethoxy dimethyl ether (DMM3-8) by a continuous acetalization reaction between an aqueous formaldehyde solution or paraformaldehyde and methanol in the presence of a functionalized acidic ionic liquid as a catalyst. The reaction system of the invention preferably comprises a formaldehyde-concentrating unit, a vacuum-drying unit, an acetalization reaction unit, a product-separating unit and a catalyst-regenerating unit. The process of the invention uses aqueous formaldehyde solution as an initial raw material, which is concentrated in the formaldehyde-concentrating unit to a concentrated formaldehyde of 50˜80 wt. %, and vacuum-dried to paraformaldehyde, or uses paraformaldehyde as raw material directly, then obtains DMM3-8 by an acetalization reaction.

Abstract: A reaction system and method for producing polyoxymethylene dialkyl ethers (RO(CH2O)nR, n=1-8) by continuous acetalation of formaldehyde and aliphatic alcohol in the presence of an acid ionic liquid catalyst. The reaction system includes an acetalation reaction unit, a product separation unit, and a catalyst regeneration unit. The recyclable material and catalyst are separated by combining extraction and rectification, and a recovery rate of more than 99% for the catalyst is achieved. Water, as the byproduct, is separated from the reaction system by destroying the azeotrope of water, alcohol, aldehyde, and RO(CH2O)nR, so that the product separation and catalyst regeneration are facilitated and the catalytic cycle is achieved.

Abstract: The invention relates to a reaction system and process for continuously preparing polymethoxy dimethyl ether (DMM3-8) by a continuous acetalization reaction between an aqueous formaldehyde solution or paraformaldehyde and methanol in the presence of a functionalized acidic ionic liquid as a catalyst. The reaction system of the invention preferably comprises a formaldehyde-concentrating unit, a vacuum-drying unit, an acetalization reaction unit, a product-separating unit and a catalyst-regenerating unit. The process of the invention uses aqueous formaldehyde solution as an initial raw material, which is concentrated in the formaldehyde-concentrating unit to a concentrated formaldehyde of 50˜80 wt. %, and vacuum-dried to paraformaldehyde, or uses paraformaldehyde as raw material directly, then obtains DMM3-8 by an acetalization reaction.

Abstract: It is disclosed a method for preparing polyoxymethylene dimethyl ethers by continuous polymerization and acetalation reactions. The method may include two steps: performing a polymerization reaction of an aqueous formaldehyde solution under catalysis of an ionic liquid IL I to obtain a mixed aqueous solution of trioxymethylene and formaldehyde; and an acetalation reaction of the mixed aqueous solution of trioxymethylene and formaldehyde with methanol is performed under catalysis of an ionic liquid IL II to prepare polyoxymethylene dimethyl ethers. The method may use an aqueous formaldehyde solution as a starting material to prepare polyoxymethylene dimethyl ethers by continuous polymerization and acetalation reactions, achieving a high use ratio of formaldehyde. A film evaporator is used in the invention, realizing a rapid separation and recycling of the light components, with a high separation efficiency. The separation of the catalyst is simple, thereby realizing recycling of the catalyst.

Abstract: A process for producing N-methyl or N,N-dimethyl amines, which comprises using amine compound, nitro-containing compound or nitrile compound as a starting material, carbon dioxide as a methylating agent and hydrogen gas as a reducing agent, and allowing them to react in a sealed reactor for 6 to 48 h in a reaction medium at a reaction temperature of 80 to 180 ° C. in the presence of a composite catalyst, so as to provide N-methyl or N,N-dimethyl amines. The process of the present invention is simple and under relative mild reaction conditions. By means of the process of the invention, the target products can be prepared at low cost with a high yield. The catalysts used have a high catalytic activity and can be separated from the reaction system simply and reused. Furthermore, the whole process of the present invention is environmental-friendly and facilitates the cycling use of carbon dioxide.

Abstract: A production process for substituted phenylacetic acids or ester analogs thereof is disclosed. In this process toluene or toluene substituted with various substituents, an alcohol, an oxidant and carbon monoxide are used as raw materials to obtain compounds comprising structure of phenylacetic acid ester or analogs thereof by catalysis of the complex catalyst formed from transition metal and ligand, and such compounds are hydrolyzed to obtain various substituted phenylacetic acid based compounds. This type of compounds and their derivatives serve as important fine chemicals used widely in the industries of pharmaceuticals, pesticides, perfume and the like.

Abstract: The invention relates to a method for producing a N-substituted amine compound by catalyzed alkylation. The method uses amine and alcohol or two kinds of amines as the reaction materials, employs composite metal oxides catalyst at a reaction temperature of 80-180° C. to catalyze the reaction for 6-36 hours, so as to produce the N-substituted amine compound. The reaction condition of the method of the invention is relatively moderate, using a catalyst made of cheap non-noble metals, which is non-caustic and easy to be separated and reused. The reaction does not need any medium and has relatively high conversion rate and selectivity.

Abstract: It is related to a method for preparing polyoxymethylene dimethyl ethers by a continuous acetalation reaction of trioxymethylene and methanol or methylal catalyzed by an ionic liquid. The processing apparatus used in the method includes a reaction zone, a separation zone, a catalyst regeneration zone and a product dehydration zone. A manner of circulating tubular reaction is used, resulting in a high external heat exchange efficiency, a simple structure of design and a low investment. A film evaporator is used, realizing a rapid separation and recycling of the light component, with a high separation efficiency. The separation of the catalyst solution from the crude product is simple, thereby realizing the regeneration and recycling of the catalyst.

Abstract: The present invention discloses a method for preparing isocyanates by liquid-phase catalytic thermal cracking. In this method, in a reaction-rectification thermal cracking reactor, using a catalyst composition comprising a superfine powder metal oxide catalyst and an ionic liquid, an alkyl or aryl dialkylurethane, or multialkylurethane being a reactant is liquid-phase thermal cracked for a reaction time of 0.5-3 h under a reaction temperature of 160-220° C. and an absolute pressure of 1000-8000 Pa so as to prepare the corresponding isocyanate. The invention has the characteristics of low thermal cracking temperature, high yield of target products, relatively simple reaction apparatus and good universality for substrates (the yields of HDI, MDI, TDI, HMDI, NDI and IPDI or the like are all>85%) and the like.

Abstract: A system and method for producing polyoxymethylene dimethyl ethers (DMMn) using an aqueous formaldehyde solution as the initial reaction material. The process system has a polymerization reaction unit, an acetalation unit, a product separation unit, and a catalyst regeneration unit. Both polymerization and acetalation reaction are conducted in the presence of an ionic liquid as a catalyst, which can achieve the effect that two different reactions may be catalyzed by the same ionic liquid. The present invention employs a simple catalyst system, and achieves the efficient separation of the catalyst, the byproduct water, the product and the reaction materials in a separation manner combining the extraction and the rectification.