Patents Assigned to LARIX BIOSCIENCE, LLC
  • METHODS AND COMPOSITIONS FOR PRODUCING DOUBLE ALLELE KNOCK OUTS
    Publication number: 20210108190
    Abstract: The present invention provides a method and compositions utilizing the CRISPR system to disrupt a target gene in eukaryotic cells to produce double allele knock outs. The method finds use in producing afucosylated antibodies with enhanced ADCC activity.
    Type: Application
    Filed: May 19, 2017
    Publication date: April 15, 2021
    Applicant: LARIX BIOSCIENCE, LLC
    Inventors: Bo Yu, James Larrick
  • METHODS AND COMPOSITIONS FOR PRODUCING DOUBLE ALLELE KNOCK OUTS
    Publication number: 20180334665
    Abstract: The present invention provides a method and compositions utilizing the CRISPR system to disrupt a target gene in eukaryotic cells to produce double allele knock outs. The method finds use in producing afucosylated antibodies with enhanced ADCC activity.
    Type: Application
    Filed: May 19, 2017
    Publication date: November 22, 2018
    Applicant: LARIX BIOSCIENCE, LLC
    Inventors: Bo Yu, James Larrick
  • METHODS AND COMPOSITIONS FOR PRODUCING DOUBLE ALLELE KNOCK OUTS
    Publication number: 20150024500
    Abstract: The present invention provides a method and compositions utilizing the CRISPR system to disrupt a target gene in eukaryotic cells to produce double allele knock outs. The method finds use in producing afucosylated antibodies with enhanced ADCC activity.
    Type: Application
    Filed: July 19, 2014
    Publication date: January 22, 2015
    Applicant: LARIX BIOSCIENCE, LLC
    Inventors: Bo Yu, James Larrick