Abstract: According to one embodiment of this disclosure, a method is provided that includes obtaining mole image information; detecting a particular mole from among the one or more moles based on the mole image information to provide particular mole image information; obtaining mole diameter information; analyzing the particular mole image information to determine (i) whether the particular mole is substantially asymmetrical, (ii) whether a border of the particular mole is substantially circular, and (iii) whether the particular mole comprises one or more substantially different colors to provide asymmetry, border, and color (ABC) analysis data; analyzing the mole diameter information to determine whether an estimated diameter of the particular mole exceeds a predetermined threshold to provide diameter (D) analysis data; and generating a plurality of melanoma risk assessments for the particular mole based on at least the ABC analysis data and the D analysis data.