Abstract: The present invention provides a method of treating or preventing a disorder typified by an immunodificiency (e.g. HIV), wherein the patient is administered a COX-2 inhibitor or derivative or pharmaceutically acceptable salt thereof, preferably diisopropylfluorophasphate. L-745337, rofecoxib, NS 398, SC 58125, etodolac, meloxicam, celecoxib or nimesulide, and compositions and products containing the same or use of the same in preparing medicaments and for treatment.
Type:
Grant
Filed:
July 20, 2001
Date of Patent:
September 7, 2010
Assignee:
Lauras AS
Inventors:
Kjetil Taskén, Michel Moutschen, Souad Rahmouni-Piette, Einar Martin Aandahl, Pål Aukrust, Stig S. Frøland, Christian C. Johansson, Vidar Hansson, Jo Klaveness
Abstract: This invention provides novel 8-carbyl substituted Camps (adenosine 3?,5?-cyclic monophosphorothioate) and a novel procedures for the preparation of 8-Br-cAMP, a key starting material.
Abstract: Pharmaceutical compositions useful for treating immunosuppressive disease and containing compounds capable of inhibiting cAMP-dependent protein kinase A (PKA) as well as use of the same, are described.
Type:
Grant
Filed:
October 28, 1999
Date of Patent:
March 20, 2007
Assignee:
Lauras AS
Inventors:
Kjetil Taskén, Einar M. Aandahl, Pål Aukrust, Bjørn S. Skålhegg, Fredrik Müller, Stig Frøland, Vidar Hansson