Patents Assigned to Laurus Labs Private Limited
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Patent number: 9567292Abstract: The present invention relates to one pot process for the preparation of 2,3-dihydroxy benzonitrile from 2,3-dialkoxy benzoic acid without prior isolation of the intermediates. Further the invention relates to the preparation of 2,3-dihydroxy benzonitrile by dealkylation of 2,3-dialkoxy benzonitrile using suitable aluminum salt-amine complex.Type: GrantFiled: July 18, 2013Date of Patent: February 14, 2017Assignee: Laurus Labs Private LimitedInventors: Hari Krishna Mudduluru, Shankar Madhavaram
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Publication number: 20160333026Abstract: The present invention relates to a novel process for the preparation of dolutegravir and pharmaceutically acceptable salts thereof using novel intermediates.Type: ApplicationFiled: January 20, 2015Publication date: November 17, 2016Applicant: Laurus Labs Private LimitedInventors: Satyanarayana CHAVA, Seeta Rama Anjaneyulu GORANTLA, Venkata Lakshmi Narasimha DAMMALAPATI, Mani Bushan Kotala, Ravindra ADURI
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Patent number: 9487487Abstract: Disclosed is a process for the preparation of montelukast sodium. The process comprises a) reacting 2-(2-(3(S)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-hydroxypropyl)phenyl)-2-propanol with methane sulfonyl chloride and coupling the resultant mesylate compound with 1-(mercaptomethyl)cyclopropane acetic acid in presence of a base and free alkali source followed by saltification with an amine in a single step reaction and b) converting the montelukast amine salt to montelukast sodium salt.Type: GrantFiled: May 17, 2013Date of Patent: November 8, 2016Assignee: LAURUS LABS PRIVATE LIMITEDInventors: Srinivas Simhadri, Yaseen Mohammad, Venkata S. Indukuri, Seeta R. Gorantla, Satyanarayana Chava
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Patent number: 9475821Abstract: Provided are a process for preparation of darunavir or solvates or a pharmaceutically acceptable salt thereof substantially free of bisfuranyl impurities and a process for preparation of amorphous darunavir using the darunavir propionate solvate.Type: GrantFiled: July 23, 2013Date of Patent: October 25, 2016Assignee: Laurus Labs Private LimitedInventors: Kameswar R. Chivukula, Venkata R. Murthy, Venkata S. Indukuri, Seeta R. Gorantla
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Patent number: 9388113Abstract: The present invention relates to pharmaceutically acceptable acid addition salts of sitagliptin, in particular anti-oxidant acid addition salts of sitagliptin and a process for its preparation. The present invention also provides a pharmaceutical composition using the pharmaceutically acceptable acid addition salts of sitagliptin.Type: GrantFiled: October 1, 2015Date of Patent: July 12, 2016Assignee: Laurus Labs Private LimitedInventors: Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla, Vamsee Krishna Muppidi, Satyanarayana Chava
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Patent number: 9382207Abstract: The present invention relates to an improved process for the preparation of Atazanavir bisulfate Form A. The present invention also relates to a pharmaceutical composition using the Atazanavir bisulfate Form A of the invention.Type: GrantFiled: August 22, 2013Date of Patent: July 5, 2016Assignee: Laurus Labs Private LimitedInventors: Srinivas Simhadri, Yaseen Mohammad, Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla
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Patent number: 9156756Abstract: An efficient method to induce the enantioselectivity in procarbonyl compounds using chiral organometallic complexes. The present invention is also described a method for producing organo metallic complexes using a base and a metal halide.Type: GrantFiled: July 30, 2008Date of Patent: October 13, 2015Assignee: Laurus Labs Private LimitedInventors: Chava Satyanarayana, Bollu Ravindra Babu
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Patent number: 9073817Abstract: The present invention provides an efficient method to induce the enantioselectivity in procarbonyl compounds using chiral organometallic complexes. The present invention also provides a method for producing chiral organometallic complexes using a chiral additive, achiral additive, a base and a metal salt.Type: GrantFiled: June 22, 2012Date of Patent: July 7, 2015Assignee: Laurus Labs Private LimitedInventors: Ravindra Babu Bollu, Narasimha Rao Ketavarapu, Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla, Satyanarayana Chava
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Publication number: 20150175532Abstract: The present invention relates to one pot process for the preparation of 2,3-dihydroxy benzonitrile from 2,3-dialkoxy benzoic acid without prior isolation of the intermediates. Further the invention relates to the preparation of 2,3-dihydroxy benzonitrile by dealkylation of 2,3-dialkoxy benzonitrile using suitable aluminum salt-amine complex.Type: ApplicationFiled: July 18, 2013Publication date: June 25, 2015Applicant: Laurus Labs Private LimitedInventors: Hari Krishna Mudduluru, Shankar Madhavaram
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Publication number: 20150031921Abstract: A process for the preparation of polyhydroxystilbene compounds (particularly resveratrol, oxyresveratrol, piceatannol, gnetol and the like) by deprotection of the corresponding ethers using aluminium halide and a secondary amine is provided.Type: ApplicationFiled: November 30, 2012Publication date: January 29, 2015Applicant: LAURUS LABS PRIVATE LIMITEDInventors: Harish Niranjanlal Dorwal, Sandirane Sabapathy, Seeta Raman Gorantla, Satyanarayana Chava
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Publication number: 20140303368Abstract: The present invention provides a process for preparation of tenofovir by dealkylation of its phosphonate ester using Ionic complexes. The present invention also provides a process for preparation of tenofovir disoproxil or a salt thereof using the tenofovir of the present invention.Type: ApplicationFiled: November 15, 2012Publication date: October 9, 2014Applicant: Laurus Labs Private LimitedInventors: Venkata Sunil Kumar Indukuri, Sree Rambabu Joga, Seeta Ramanjaneyulu Gorantla, Satyanarayana Chava
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Patent number: 8791259Abstract: The present invention provides a process for the preparation of tenofovir. The present invention also provides a process for the preparation of tenofovir disoproxil or a salt thereof and its pharmaceutical composition using the tenofovir of the present invention.Type: GrantFiled: November 26, 2012Date of Patent: July 29, 2014Assignee: Laurus Labs Private LimitedInventors: Satyanarayana Chava, Seeta Ramanjaneyulu Gorantla, Venkata Sunil Kumar Indukuri, Sree Rambabu Joga
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Publication number: 20140163203Abstract: The present invention provides processes for preparation of eptifibatide that involve coupling of amino acids in a (2+5), (4+3) and (3+4) sequence method. The invention further provides products produced by the described processes, novel compounds that can be used as synthetic intermediates for the preparation of eptifibatide.Type: ApplicationFiled: July 26, 2012Publication date: June 12, 2014Applicant: Laurus Labs Private LimitedInventors: Subha Nair Velayudhan, Bollu R. Babu, Venkata S. Indukuri, Seeta R. Gorantla, Venkata S. Ramakrishna, Bala M. Madivada
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Publication number: 20140094475Abstract: Disclosed are solid forms of antiretroviral compounds and anti-oxidative acids, and processes for their preparation. Pharmaceutical compositions using the solid forms are also disclosed.Type: ApplicationFiled: April 9, 2012Publication date: April 3, 2014Applicant: LAURUS LABS PRIVATE LIMITEDInventors: Venkata S. Indukuri, Vamsee K. Muppidi, Sree R. Joga, Seeta R. Gorantla, Satyanarayana Chava
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Publication number: 20140073791Abstract: The present invention relates to pharmaceutically acceptable acid addition salts of sitagliptin, in particular anti-oxidant acid addition salts of sitagliptin and a process for its preparation. The present invention also provides a pharmaceutical composition using the pharmaceutically acceptable acid addition salts of sitagliptin.Type: ApplicationFiled: October 12, 2012Publication date: March 13, 2014Applicant: LAURUS LABS PRIVATE LIMITEDInventors: Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla, Vamsee Krishna Muppidi, Satyanarayana Chava
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Publication number: 20140031352Abstract: The present invention generally relates to solid forms of tyrosine kinase inhibitors, in particular combinations of tyrosine kinase inhibitors with anti-oxidative acids, processes for its preparation and a pharmaceutical compositions containing the same.Type: ApplicationFiled: July 23, 2013Publication date: January 30, 2014Applicant: Laurus Labs Private LimitedInventors: Seeta Ramanjaneyulu GORANTLA, Ashwini Nangia, Krishna Sumanth Peraka, Udaya Bhaskara Rao
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Patent number: 8524782Abstract: The present invention provides a scalable process for the preparation of stilbenes by (i) condensing 3,5-dialkylbenzyl phosphonates with 4?-O-tetrahydropyranyl benzaldehyde to get 3,5-alkyl-4?-O-tetrahydropyranyl Stilbene and (ii) deprotecting the obtained 3,5-Dialkyl-4?-O-tetrahydropyranylstilbene to yield stilbenes. The present invention also provides a novel intermediate 3,5-Dialkyl-4?-O-tetrahydropyranyl stilbene, which is a key intermediate for the synthesis of stilbenes such as Pterostilbene and Resveratrol. The present invention also provides characteristics of various solid forms of Pterostilbene, methods for their preparation, as well as dosage forms containing the same for administration to or consumption by humans.Type: GrantFiled: January 21, 2011Date of Patent: September 3, 2013Assignee: Laurus Labs Private LimitedInventors: Gottumukkala V. Subbaraju, Masna Mahesh, Hindupur R. Mohan, Thatipally Suresh, Igor Ivanisevic, Mark Andres, Kyle Stephens
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Patent number: 8513236Abstract: Cocrystals of pterostilbene are disclosed, including: pterostilbene:caffeine cocrystal, pterostilbene:carbamazepine cocrystal, pterostilbene:glutaric acid cocrystal, and pterostilbene:piperazine cocrystal. The pterostilbene:caffeine cocrystal is polymorphic. Forms I and II of the pterostilbene:caffeine cocrystal are disclosed. The therapeutic uses of the pterostilbene cocrystals and of pharmaceutical/nutraceutical compositions containing them are also disclosed. The disclosure sets out various methods of making and characterizing the pterostilbene cocrystals.Type: GrantFiled: July 30, 2010Date of Patent: August 20, 2013Assignee: Laurus Labs Private LimitedInventors: Nathan C. Schultheiss, Sarah J. Bethune
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Patent number: 8415507Abstract: Cocrystals of pterostilbene are disclosed, including: pterostilbene:caffeine cocrystal, pterostilbene:carbamazepine cocrystal, pterostilbene:glutaric acid cocrystal, and pterostilbene:piperazine cocrystal. The pterostilbene:caffeine cocrystal is polymorphic. Forms I and II of the pterostilbene:caffeine cocrystal are disclosed. The therapeutic uses of the pterostilbene cocrystals and of pharmaceutical/nutraceutical compositions containing them are also disclosed. The disclosure sets out various methods of making and characterizing the pterostilbene cocrystals.Type: GrantFiled: July 30, 2010Date of Patent: April 9, 2013Assignee: Laurus Labs Private LimitedInventors: Nathan C. Schultheiss, Sarah J. Bethune
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Patent number: 8399712Abstract: Cocrystals of pterostilbene are disclosed, including: pterostilbene:caffeine cocrystal, pterostilbene:carbamazepine cocrystal, pterostilbene:glutaric acid cocrystal, and pterostilbene:piperazine cocrystal. The pterostilbene:caffeine cocrystal is polymorphic. Forms I and II of the pterostilbene:caffeine cocrystal are disclosed. The therapeutic uses of the pterostilbene cocrystals and of pharmaceutical/nutraceutical compositions containing them are also disclosed. The disclosure sets out various methods of making and characterizing the pterostilbene cocrystals.Type: GrantFiled: July 30, 2010Date of Patent: March 19, 2013Assignee: Laurus Labs Private LimitedInventors: Nathan C. Schultheiss, Sarah J. Bethune