Patents Assigned to Laurus Labs Private Ltd.
  • Diastereoselective synthesis of phosphate derivatives
    Patent number: 10774104
    Abstract: Disclosed is a method for the preparation of intermediates useful in the synthesis of gemcitabine-[phenyl-benzoxy-L-alaninyl)]-phosphate. Also disclosed is a method of preparing gemcitabine-[phenyl-benzoxy-L-alaninyl)]-phosphate.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: September 15, 2020
    Assignee: Laurus Labs Private Ltd
    Inventors: Mani Bushan Kotala, Venkata Lakshmi Narasimha Rao Dammalapati
  • PROCESS FOR THE PREPARATION OF GEMCITABINE-[PHENYL(BENZOXY-L-ALANINYL)] PHOSPHATE
    Publication number: 20170166602
    Abstract: The present invention provides a process for the preparation of gemcitabine-[phenyl(benzoxy-L-alaninyl)] phosphate of Formula I in high yield and purity.
    Type: Application
    Filed: July 22, 2015
    Publication date: June 15, 2017
    Applicants: NuCana Biomed Limited, Laurus Labs Private Ltd.
    Inventors: Venkata Lakshmi Narasimha Rao Dammalapati, Mani Bushan Kotala, Shankar Madhavaram
  • Solid forms of antiretroviral compounds, process for the preparation and their pharmaceutical composition thereof
    Patent number: 9650346
    Abstract: Disclosed are solid forms of antiretroviral compounds and anti-oxidative acids, and processes for their preparation. Pharmaceutical compositions using the solid forms are also disclosed.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: May 16, 2017
    Assignee: Laurus Labs Private Ltd.
    Inventors: Venkata S. Indukuri, Vamsee K. Muppidi, Sree R. Joga, Seeta R. Gorantla, Satyanarayana Chava
  • Process for the preparation of Ivacaftor and its intermediates
    Patent number: 9573902
    Abstract: The present invention provides novel intermediates of ivacaftor and process for its preparation. The present invention also provides process for the preparation of ivacaftor and pharmaceutically acceptable salt thereof using novel intermediates.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: February 21, 2017
    Assignee: LAURUS LABS PRIVATE LTD.
    Inventors: Suresh Thatipally, Venkata Lakshmi Narasimha Rao Dammalapati, Seeta Ramanjaneyulu Gorantla, Satyanarayana Chava
  • Process for the preparation of sunitinib and its acid addition salts thereof
    Patent number: 9206163
    Abstract: The present invention relates to an improved process for the preparation of Sunitinb. The process involves the activation of 5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene) methyl)-2,4-dimethyl-1 H-pyrrole-3carboxylic acid to corresponding suitable carboxylic acid activating group. The present invention also relates to novel acid addition salts of Sunitinb and preparation thereof.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: December 8, 2015
    Assignee: Laurus Labs Private Ltd.
    Inventors: Sanjay Kumar Dehury, Venkata Lakshmi Narasimha Dammalapati, Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla
  • Salts of sitagliptin, process for the preparation and pharmaceutical composition therefore
    Patent number: 9181256
    Abstract: The present invention relates to pharmaceutically acceptable acid addition salts of sitagliptin, in particular anti-oxidant acid addition salts of sitagliptin and a process for its preparation. The present invention also provides a pharmaceutical composition using the pharmaceutically acceptable acid addition salts of sitagliptin.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: November 10, 2015
    Assignee: Laurus Labs Private Ltd.
    Inventors: Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla, Vamsee Krishna Muppidi, Satyanarayana Chava
  • Process for preparing eptifibatide
    Patent number: 9156885
    Abstract: The present invention provides processes for preparation of eptifibatide that involve coupling of amino acids in a (2+5), (4+3) and (3+4) sequence method. The invention further provides products produced by the described processes, novel compounds that can be used as synthetic intermediates for the preparation of eptifibatide.
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: October 13, 2015
    Assignee: Laurus Labs Private Ltd.
    Inventors: Subha Nair Velayudhan, Ravindra Babu Bollu, Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla, Venkata Siva RamaKrishna Reddy Kallam, Bala Muralikrishna Madivada
  • Process for the preparation of tenofovir
    Patent number: 9056882
    Abstract: The present invention provides a process for preparation of tenofovir by dealkylation of its phosphonate ester using Ionic complexes. The present invention also provides a process for preparation of tenofovir disoproxil or a salt thereof using the tenofovir of the present invention.
    Type: Grant
    Filed: November 15, 2012
    Date of Patent: June 16, 2015
    Assignee: Laurus Labs Private Ltd.
    Inventors: Venkata Sunil Kumar Indukuri, Sree Rambabu Joga, Seeta Ramanjaneyulu Gorantla, Satyanarayana Chava
  • Process for the preparation of polyhydroxystilbene compounds by deprotection of the corresponding ethers
    Patent number: 8987525
    Abstract: A process for the preparation of polyhydroxystilbene compounds (particularly resveratrol, oxyresveratrol, piceatannol, gnetol and the like) by deprotection of the corresponding ethers using aluminum halide and a secondary amine is provided.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: March 24, 2015
    Assignee: Laurus Labs Private Ltd.
    Inventors: Harish Niranjanlal Dorwal, Sandirane Sabapathy, Seeta Raman Gorantla, Satyanarayana Chava