Patents Assigned to LEADGENE BIOMEDICAL, INC.
  • Isolated monoclonal antibodies and/or antigen-binding fragments thereof against indoxyl sulfate and uses thereof
    Patent number: 11560423
    Abstract: The present invention relates to isolated monoclonal antibodies (mAbs) and/or antigen-binding fragments thereof that specifically recognize indoxyl sulfate, a protein-bound uremic toxin, and uses of such isolated anti-IS mAbs and/or antigen-binding fragments thereof to create immunoassay methods applied in theragnosis of IS-related diseases.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: January 24, 2023
    Assignee: LEADGENE BIOMEDICAL, INC.
    Inventors: Yung-Chun Chuang, Yu-Wei Cheng, Chih-Hui Kao
  • Compositions of isolated monoclonal antibodies and/or antigen-binding fragments thereof against indoxyl sulfate and uses thereof
    Patent number: 10723791
    Abstract: The present invention relates to isolated monoclonal antibodies (mAbs) and/or antigen-binding fragments thereof that specifically recognize indoxyl sulfate, a protein-bound uremic toxin, isolated polynucleotide segment encoding the isolated antibodies and/or antigen-binding fragments thereof, and uses of such isolated anti-IS mAbs and/or antigen-binding fragments thereof to create immunoassay methods, device compositions, and pharmaceutical compositions applied in theragnosis of IS-related diseases.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: July 28, 2020
    Assignee: LEADGENE BIOMEDICAL, INC.
    Inventors: Yung-Chun Chuang, Yu-Wei Cheng, Chih-Hui Kao
  • COMPOSITIONS OF ISOLATED MONOCLONAL ANTIBODIES AND/OR ANTIGEN-BINDING FRAGMENTS THEREOF AGAINST INDOXYL SULFATE AND USES THEREOF
    Publication number: 20200031909
    Abstract: The present invention relates to isolated monoclonal antibodies (mAbs) and/or antigen-binding fragments thereof that specifically recognize indoxyl sulfate, a protein-bound uremic toxin, isolated polynucleotide segment encoding the isolated antibodies and/or antigen-binding fragments thereof, and uses of such isolated anti-IS mAbs and/or antigen-binding fragments thereof to create immunoassay methods, device compositions, and pharmaceutical compositions applied in theragnosis of IS-related diseases.
    Type: Application
    Filed: April 18, 2019
    Publication date: January 30, 2020
    Applicant: LEADGENE BIOMEDICAL, INC.
    Inventors: Yung-Chun CHUANG, Yu-Wei CHENG, Chih-Hui KAO