Patents Assigned to Legend Biotech Ireland Limited
  • Single-domain antibodies against CLL1 and constructs thereof
    Patent number: 12097219
    Abstract: Provided are single-domain antibodies targeting CLL1 and constructs thereof, including chimeric receptors, immune effector cell engagers and immunoconjugates. Further provided are engineered immune effector cells (such as T cells) comprising an anti-CLL1 chimeric receptor and optionally a second chimeric receptor targeting a second antigen or epitope. Pharmaceutical compositions, kits and methods of treating cancer are also provided.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: September 24, 2024
    Assignee: Legend Biotech Ireland Limited
    Inventors: Wang Zhang, Yunlei Liu, Xiaojie Tu, Chenyu Shu, Tailan Zhan, Yun Zhang, An Tang, Yafeng Zhang, Shu Wu, Qing Zhang