Patents Assigned to Lein Applied Diagnostics Limited
-
Patent number: 9952394Abstract: An optical measurement apparatus (102) containing a bidirectional optical transceiver component (200), the bidirectonal optical transceiver component (200) comprising a source of optical electromagnetic radiation (208), an optical detector (214), a beamsplitter, and a combined input and output port (218). The port (218) is arranged to permit, when in use, propagation of optical electromagnetic radiation therethrough. The beamsplitter is aligned within a housing (206) with respect to the optical source (208), the optical detector (214) and the port (218) in order to direct optical electromagnetic radiation emitted by the optical source (214) to the port (214) and to direct optical electromagnetic radiation received from the port (214) to the optical detector (208).Type: GrantFiled: November 26, 2013Date of Patent: April 24, 2018Assignee: Lein Applied Diagnostics LimitedInventors: Robin Taylor, James Reynolds, Simon Meadowcroft
-
Patent number: 8552892Abstract: A signal sample trigger apparatus (206) comprises an input (302, 304), a processing resource (300, 500) coupled to the input (302, 304), and an output (306) coupled to the processing resource (300, 500). The processing resource (300, 500) is arranged to generate, when in use, a trigger signal (400, 600) in response to location increment information. The location increment information (402, 404, 602, 604) is received via the input (302, 304), and the trigger signal (400, 600) is provided via the output for triggering execution of a sample of an analogue signal.Type: GrantFiled: January 25, 2010Date of Patent: October 8, 2013Assignee: Lein Applied Diagnostics LimitedInventor: Robin Taylor
-
Publication number: 20120179380Abstract: A measurement apparatus comprises a probe system (100) operably coupled, when in use, to a processing resource (134). The probe system (100) and the processing resource (134) are arranged, when in use, to measure an apparent thickness change of a volume of the medium (108) to be measured and to determine a physiological parameter using the measurement of the apparent thickness change.Type: ApplicationFiled: February 9, 2009Publication date: July 12, 2012Applicant: Lein Applied Diagnostics LimitedInventors: Robin Taylor, Richard Holley, Austen Hearn
-
Patent number: 8078245Abstract: A method and apparatus for measuring an apparent depth of a section of an animal body are disclosed. Light is focused concurrently to an extended focal region comprising a plurality or continuum of measurement locations. Light reflected by a refractive index interface coincident with one of the plurality of measurement locations is detected. Detected light signals are generated from light reflected from first and second interfaces respectively defining the section under investigation, so that the apparent positions of the interfaces may be derived. A confocal arrangement and an axicon element may be employed. Preferably, the section is the aqueous humor of an eye. From changes in its refractive index corresponding changes in glucose concentration in the aqueous humor and, in turn, in the bloodstream of a patient may be derived, offering a non-invasive monitoring means for diabetic patients. Other compounds and structures of the body may alternatively be investigated.Type: GrantFiled: November 24, 2004Date of Patent: December 13, 2011Assignee: Lein Applied Diagnostics LimitedInventors: Daniel John Daly, Graeme Lawrence Clark
-
Publication number: 20110291743Abstract: A signal sample trigger apparatus (206) comprises an input (302, 304), a processing resource (300, 500) coupled to the input (302, 304), and an output (306) coupled to the processing resource (300, 500). The processing resource (300, 500) is arranged to generate, when in use, a trigger signal (400, 600) in response to location increment information. The location increment information (402, 404, 602, 604) is received via the input (302, 304), and the trigger signal (400, 600) is provided via the output for triggering execution of a sample of an analogue signal.Type: ApplicationFiled: January 25, 2010Publication date: December 1, 2011Applicant: Lein Applied Diagnostics LimitedInventor: Robin Taylor
-
Patent number: 7769419Abstract: A method and apparatus for measuring an apparent depth (1) of a section of an eye (30) are disclosed. Light is focused to a measurement location (15) proximate or within the eye. The measurement location is scanned through the section and upon passing through first and second refractive index interfaces defining the section, a respective reflected light signal is detected, from which apparent positions of the first and second interfaces may be derived. Preferably, a confocal scanning arrangement is employed. Preferably, the section is the aqueous humor (34) of the eye (30). From changes in its refractive index (n) corresponding changes in glucose concentration in the aqueous humor and, in turn, in the bloodstream of a patient may be derived, offering a non-invasive monitoring means for diabetic patients. The apparatus may be a hand-held device, employing microelectromechanical systems.Type: GrantFiled: October 20, 2004Date of Patent: August 3, 2010Assignee: Lein Applied Diagnostics LimitedInventor: Daniel John Daly
-
Publication number: 20070078308Abstract: A method and apparatus for measuring an apparent depth (1) of a section of an eye (30) are disclosed. Light is focused to a measurement location (15) proximate or within the eye. The measurement location is scanned through the section and upon passing through first and second refractive index interfaces defining the section, a respective reflected light signal is detected, from which apparent positions of the first and second interfaces may be derived. Preferably, a confocal scanning arrangement is employed. Preferably, the section is the aqueous humor (34) of the eye (30). From changes in its refractive index (n) corresponding changes in glucose concentration in the aqueous humor and, in turn, in the bloodstream of a patient may be derived, offering a non-invasive monitoring means for diabetic patients. The apparatus may be a hand-held device, employing microelectromechanical systems.Type: ApplicationFiled: October 20, 2004Publication date: April 5, 2007Applicant: Lein Applied Diagnostics LimitedInventor: Daniel Daly