Patents Assigned to LENZ THERAPEUTICS, INC.
  • Compositions and methods for the treatment of presbyopia
    Patent number: 11648247
    Abstract: The present invention is directed to compositions for and methods for the treatment of presbyopia comprising from about 0.3% to about 2.0% w/v aceclidine and from about 0.07% to about 0.15% w/v brimonidine.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: May 16, 2023
    Assignee: Lenz Therapeutics, Inc.
    Inventor: Gerald Horn
  • Methods for the treatment of myopia
    Patent number: 11344538
    Abstract: The invention provides methods for the treatment of myopia. The compositions preferably comprise aceclidine. The compositions optionally contain a surfactant, a viscosity agent, a polyol and/or a selective ?-2 adrenergic receptor agonist.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: May 31, 2022
    Assignee: LENZ THERAPEUTICS, INC.
    Inventor: Gerald Horn
  • Compositions and methods for the treatment of presbyopia
    Patent number: 11273150
    Abstract: The invention provides compositions and methods for the treatment of presbyopia. The methods preferably comprise storing an aceclidine composition in a container having a headspace at a temperature from about 2 to about 8 degrees Celsius. The methods further comprise filling the container under an inert gas overlay and/or enclosing the container an anti-leaching material or disposing the container in a second container containing an anti-leaching material.
    Type: Grant
    Filed: October 13, 2020
    Date of Patent: March 15, 2022
    Assignee: LENZ THERAPEUTICS, INC.
    Inventor: Gerald Horn
  • Prodrugs of quinuclidine ring-containing muscarinic agonists and compositions and methods thereof
    Patent number: 11214569
    Abstract: The present invention is directed to compounds of the formula and salts or esters thereof. The present invention is further directed to ophthalmological compositions comprising a therapeutically effective amount of a compound of the present invention and one or more pharmaceutically acceptable excipients. The present invention is further directed to a methods of treating presbyopia or glaucoma or reducing hyperemia comprising administering to a patient in need thereof a therapeutically effective amount of a compound of the present invention.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: January 4, 2022
    Assignee: LENZ THERAPEUTICS, INC.
    Inventor: Gerald Horn
  • Compositions and methods for the treatment of presbyopia
    Patent number: 11179327
    Abstract: The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably comprise aceclidine. The compositions optionally contain a surfactant and a viscosity agent.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: November 23, 2021
    Assignee: LENZ THERAPEUTICS, INC.
    Inventors: Gerald Horn, Lee Nordan
  • Compositions and methods for the treatment of presbyopia
    Patent number: 11179328
    Abstract: The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably comprise aceclidine. The compositions optionally contain a surfactant and a viscosity agent.
    Type: Grant
    Filed: January 20, 2020
    Date of Patent: November 23, 2021
    Assignee: LENZ THERAPEUTICS, INC.
    Inventor: Gerald Horn