Patents Assigned to LEPTON PHARMACEUTICALS LTD
  • METHODS FOR ENHANCING THERAPEUTIC EFFICACY OF ISOLATED CELLS FOR CELL THERAPY
    Publication number: 20240010977
    Abstract: This disclosure relates to methods for enhancing the therapeutic efficacy of isolated cells for use in cell therapies such as adoptive cell transfer therapies by insertion of an under-expressed miRNA that is beneficial for therapeutic efficacy of cell therapies into the actively expressed locus of a gene, either protein coding or non-coding, that hampers therapeutic efficacy of cell therapies by this disrupting expression of the latter while inducing expression of the former.
    Type: Application
    Filed: June 1, 2023
    Publication date: January 11, 2024
    Applicant: LEPTON PHARMACEUTICALS LTD
    Inventors: Daniel Zurr, Hagar Kalinski, Elena Feinstein