Patents Assigned to Les Hospices Civils de Lyon
  • Mutant proteins of the F protein of PIV-5 and PIV-2
    Patent number: 8926988
    Abstract: The present application concerns mutant proteins of the fusion protein (F protein) of the parainfluenza virus (PIV) which are currently indexed as type 5 PIV (PIV-5 or PIV5) and type 2 PIV (PIV-2 or PIV2). The present application concerns products deriving therefrom, such as: nucleic acids, vectors, cells, fusion inhibitors of the antibody, aptamer, interfering RNA type; myelomas, hybridomas; stem and progenitor cells. The present application also concerns mutant proteins and products derived therefrom for use in medical and biotechnological applications.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: January 6, 2015
    Assignees: Centre National de la Recherche Scientifique, Universite Claude Bernard de Lyon 1, Les Hospices Civils de Lyon
    Inventors: Manuel Melchior Jean-Pierre Rosa Calatrava, Olivier Terrier, Francois Edouard Julien Durupt
  • HPIV-2 variants and their medical applications
    Patent number: 8927701
    Abstract: A variant phylogenetic group of HPIV-2, more particularly a novel variant phylogenetic sub-group of HPIV-2, and a means for diagnosing HPIV-2 which take into account this novel group and this novel sub-group.
    Type: Grant
    Filed: July 18, 2008
    Date of Patent: January 6, 2015
    Assignees: Centre National de la Recherche Scientifique, Les Hospices Civils de Lyon
    Inventors: Bruno Lina, Olivier Terrier, Danielle Françoise Thouvenot
  • Mutant proteins of the F protein of PIV-5 and PIV-2
    Patent number: 8906386
    Abstract: The present application concerns mutant proteins of the fusion protein (F protein) of the parainfluenza virus (PIV) which are currently indexed as type 5 PIV (PIV-5 or PIV5) and type 2 PIV (PIV-2 or PIV2). The present application concerns products deriving therefrom, such as: nucleic acids, vectors, cells, fusion inhibitors of the antibody, aptamer, interfering RNA type; myelomas, hybridomas; stem and progenitor cells. The present application also concerns mutant proteins and products derived therefrom for use in medical and biotechnological applications.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: December 9, 2014
    Assignees: Centre National de la Recherche Scientifique, Universite Claude Bernard de Lyon 1, Les Hospices Civils de Lyon
    Inventors: Manuel Melchior Jean-Pierre Rosa Calatrava, Olivier Terrier, Francois Edouard Julien Durupt
  • MUTANT PROTEINS OF THE F PROTEIN OF PIV-5 AND PIV-2
    Publication number: 20110318355
    Abstract: The present application concerns mutant proteins of the fusion protein (F protein) of the parainfluenza virus (PIV) which are currently indexed as type 5 PIV (PIV-5 or PIV5) and type 2 PIV (PIV-2 or PIV2). The present application concerns products deriving therefrom, such as: nucleic acids, vectors, cells, fusion inhibitors of the antibody, aptamer, interfering RNA type; myelomas, hybridomas; stem and progenitor cells. The present application also concerns mutant proteins and products derived therefrom for use in medical and biotechnological applications.
    Type: Application
    Filed: November 17, 2009
    Publication date: December 29, 2011
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, LES HOSPICES CIVILS DE LYON, UNIVERSITE CLAUDE BERNARD DE LYON 1
    Inventors: Manuel Melchior Jean-Pierre Rosa Calatrava, Olivier Terrier, Francois Edouard Julien Durupt
  • MUTANT PROTEINS OF THE F PROTEIN OF PIV-5 AND PIV-2
    Publication number: 20110311541
    Abstract: The present application concerns mutant proteins of the fusion protein (F protein) of the parainfluenza virus (PIV) which are currently indexed as type 5 PIV (PIV-5 or PIV5) and type 2 PIV (PIV-2 or PIV2). The present application concerns products deriving therefrom, such as: nucleic acids, vectors, cells, fusion inhibitors of the antibody, aptamer, interfering RNA type; myelomas, hybridomas; stem and progenitor cells. The present application also concerns mutant proteins and products derived therefrom for use in medical and biotechnological applications.
    Type: Application
    Filed: November 17, 2009
    Publication date: December 22, 2011
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, LES HOSPICES CIVILS DE LYON, UNIVERSITE CLAUDE BERNARD DE LYON 1
    Inventors: Manuel Melchior Jean-Pierre Rosa Calatrava, Olivier Terrier, Francois Edouard Julien Durupt
  • HPIV-2 VARIANTS AND THEIR MEDICAL APPLICATIONS
    Publication number: 20110077170
    Abstract: A variant phylogenetic group of HPIV-2, more particularly a novel variant phylogenetic sub-group of HPIV-2, and a means for diagnosing HPIV-2 which take into account this novel group and this novel sub-group.
    Type: Application
    Filed: July 18, 2008
    Publication date: March 31, 2011
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, LES HOSPICES CIVILS DE LYON
    Inventors: Bruno Lina, Olivier Terrier, Danielle Francoise Thouvenot
  • Functional and anatomical delivery simulator
    Patent number: 7651332
    Abstract: A delivery simulator may include a fetal system comprising at least a fetal head. The fetal system may be configured to simulate the behavior of at least one part of a fetus, a maternal system configured to simulate the behavior of at least one part of a mother's body interacting with the fetus, and a device for establishing the position of at least one point of the fetal head. The device may include at least one marker element positioned on the fetal head, and at least one fixed element linked to said marker element and placed at a distance from the fetal head.
    Type: Grant
    Filed: February 21, 2007
    Date of Patent: January 26, 2010
    Assignees: Centre National de la Recherche Scientifique, Institute National des Sciences Appliquees de Lyon, Les Hospices Civils de Lyon
    Inventors: Olivier Dupuis, Maurice Betemps, Georges Delhomme, André Dittmar, Hervé Tanneguy Redarce, Ruimark Creazzola Silveira