Patents Assigned to LEUKOCARE AG
  • Publication number: 20140134214
    Abstract: The present invention, inter alia, relates to a closed sterilized container comprising at least one carrier which is a stabilizer; and at least one biomolecule reversibly attached to the carrier, wherein said carrier partially or completely covers the attached biomolecules and wherein said at least one carrier is selected from the group consisting of (poly)peptides such as dipeptides or tripeptides, amino acids, polyalcohols, polyethyleneglycols, ionic liquids, compatible solutes, saponins and a mixture thereof. The invention also relates to methods for producing sterilized containers according to the invention and uses thereof.
    Type: Application
    Filed: January 16, 2014
    Publication date: May 15, 2014
    Applicant: Leukocare AG
    Inventors: Jens Altrichter, Anja Breuer, Nicole Schaath, Julia Quathamer
  • Publication number: 20140099697
    Abstract: The present invention relates to a method for preventing the unfolding of a (poly)peptide during drying and/or inducing the (re-)folding of a (poly)peptide after drying, comprising the step of embedding the (poly)peptide in an aqueous solution, wherein the solution comprises (i) at least three different amino acids; or (ii) at least one dipeptide or tripeptide; and wherein the solution is free or substantially free of (a) sugar; and (b-i) protein; and/or (b-ii) denaturing compounds; and (c) silanes.
    Type: Application
    Filed: June 28, 2012
    Publication date: April 10, 2014
    Applicant: Leukocare AG
    Inventors: Martin Scholz, Jens Altrichter, Kristina Kemter
  • Patent number: 8685459
    Abstract: The present invention, inter alia, relates to a closed sterilized container comprising at least one carrier which is a stabilizer; and at least one biomolecule reversibly attached to the carrier, wherein said carrier partially or completely covers the attached biomolecules and wherein said at least one carrier is selected from the group consisting of (poly)peptides such as dipeptides or tripeptides, amino acids, polyalcohols, polyethyleneglycols, ionic liquids, compatible solutes, saponins and a mixture thereof. The invention also relates to methods for producing sterilized containers according to the invention and uses thereof.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: April 1, 2014
    Assignee: Leukocare AG
    Inventors: Jens Altrichter, Anja Breuer, Nicole Schaath, Julia Quathamer
  • Publication number: 20120118825
    Abstract: The present invention relates to a method for filtering blood to produce plasma or serum and to a blood filter for the production of plasma or serum from a blood sample. The invention further relates to a kit comprising a blood filter for the production of plasma or serum from a blood sample and a syringe.
    Type: Application
    Filed: June 17, 2010
    Publication date: May 17, 2012
    Applicant: Leukocare AG
    Inventors: Stefan Margraf, Martin Scholz
  • Publication number: 20120107829
    Abstract: The present invention relates to the use of a composition comprising (a) at least three different amino acids, (b) at least two different amino acids and a saponin or (c) at least one dipeptide or tripeptide for stabilizing biomolecules immobilized on a solid carrier. The invention furthermore relates to a method for producing stabilized biomolecules, comprising embedding the biomolecules in the composition according to the invention and a method of producing a solid carrier having biomolecules attached thereto. The invention furthermore relates to a solid carrier producible or produced by the method of the invention and a method of diagnosing a disease using the carrier of the invention.
    Type: Application
    Filed: March 31, 2010
    Publication date: May 3, 2012
    Applicant: LEUKOCARE AG
    Inventors: Stefan Margraf, Anja Breuer, Martin Scholz, Jens Altrichter
  • Publication number: 20120093803
    Abstract: The present invention, inter alia, relates to a closed sterilized container comprising at least one carrier which is a stabilizer; and at least one biomolecule reversibly attached to the carrier, wherein said carrier partially or completely covers the attached biomolecules and wherein said at least one carrier is selected from the group consisting of (poly)peptides such as dipeptides or tripeptides, amino acids, polyalcohols, polyethyleneglycols, ionic liquids, compatible solutes, saponins and a mixture thereof. The invention also relates to methods for producing sterilized containers according to the invention and uses thereof.
    Type: Application
    Filed: March 31, 2010
    Publication date: April 19, 2012
    Applicant: LEUKOCARE AG
    Inventors: Jens Altrichter, Anja Breuer, Nicole Schaath, Julia Quathamer
  • Publication number: 20100291665
    Abstract: The present invention relates to a method of producing a solid coated carrier carrying biological material. Furthermore, the invention relates to a solid coated carrier to which biological material is attached and uses of the solid coated carrier for the preparation of a medical product. Moreover, the invention provides a method for the contacting, filtration or cleaning of blood, lymph or liquor cerebrospinalis of a patient, a method for the diagnosis of a disease and a diagnostic composition.
    Type: Application
    Filed: November 7, 2008
    Publication date: November 18, 2010
    Applicant: LEUKOCARE AG
    Inventors: Stefan Margraf, Martin Scholz, Jens Altrichter
  • Publication number: 20090298078
    Abstract: The present invention relates to a method for the detection of an activation of the immune system, preferably in the sense of an NET formation, or the extent of cell death in a non-tumorous tissue or in a body fluid, wherein free DNA is measured in a sample from an individual. Furthermore, the invention relates to a method for the production of a kit for the detection of an activation of the immune system or the extent of cell death in an individual, comprising the packaging of a fluorescent dye and a DNA standard in at least one container.
    Type: Application
    Filed: October 1, 2007
    Publication date: December 3, 2009
    Applicant: Leukocare AG
    Inventor: Stefan Margraf
  • Publication number: 20090269778
    Abstract: The present invention relates to a method of producing a solid coated carrier carrying biological material. Furthermore, the invention relates to a solid coated carrier to which biological material is attached and uses of the solid coated carrier for the preparation of a medical product. Moreover, the invention provides a method for the contacting, filtration or cleaning of blood, lymph or liquor cerebrospinalis of a patient, a method for the diagnosis of a disease and a diagnostic composition.
    Type: Application
    Filed: May 7, 2007
    Publication date: October 29, 2009
    Applicant: LEUKOCARE AG
    Inventors: Stefan Margraf, Martin Scholz