Abstract: The invention relates to a combination comprising an antineoplastic agent, e.g. an antimetabolite antineoplastic agent and a type 1 serotonin receptor (HTR 1)modulator, e.g. a HTR1 antagonist. In addition the invention relates to a pharmaceutical composition comprising a combination of the invention and a pharmaceutically acceptable excipient. The invention also relates to the combination and pharmaceutical composition according to the invention for use in medicine, particularly for use in the prevention and/or treatment of a hematological malignancy.
Type:
Application
Filed:
August 10, 2022
Publication date:
April 20, 2023
Applicant:
LEUKOS BIOTECH, S.L.
Inventors:
Ruth MUÑOZ RISUEÑO, Mari Carmen LARA CASTILLO, Amaia ETXABE ALBERDI
Abstract: The invention relates to a combination comprising an antineoplastic agent, e.g. an antimetabolite antineoplastic agent and a type 1 serotonin receptor (HTR1) modulator, e.g. a HTR1 antagonist. In addition the invention relates to a pharmaceutical composition comprising a combination of the invention and a pharmaceutically acceptable excipient. The invention also relates to the combination and pharmaceutical composition according to the invention for use in medicine, particularly for use in the prevention and/or treatment of a hematological malignancy.
Type:
Grant
Filed:
January 15, 2018
Date of Patent:
September 20, 2022
Assignee:
Leukos Biotech, S.L.
Inventors:
Ruth Muñoz Risueño, Mari Carmen Lara Castillo, Amaia Etxabe Alberdi
Abstract: A pharmaceutical composition comprising apomorphine (APO) in a solid crystalline form, wherein the solid crystalline form is an APO·palmitic acid cocrystal solid particle crystalline form.
Type:
Grant
Filed:
January 15, 2019
Date of Patent:
July 12, 2022
Assignee:
LEUKOS BIOTECH, S. L.
Inventors:
Enrique Llaudet Carles, Nicolas Tesson, Montserrat Trilla Castaño
Abstract: The invention relates to a combination comprising an antineoplastic agent, e.g. an antimetabolite antineoplastic agent and a type 1 serotonin receptor (HTR1) modulator, e.g. a HTR1 antagonist. In addition the invention relates to a pharmaceutical composition comprising a combination of the invention and a pharmaceutically acceptable excipient. The invention also relates to the combination and pharmaceutical composition according to the invention for use in medicine, particularly for use in the prevention and/or treatment of a hematological malignancy.
Type:
Application
Filed:
January 15, 2018
Publication date:
December 5, 2019
Applicant:
Leukos Biotech, S.L.
Inventors:
Ruth MUÑOZ RISUEÑO, Mari Carmen LARA CASTILLO, Amaia ETXABE ALBERDI