Abstract: Various fabrics, compression garments and compression garment systems are described. Fabrics formed from wicking and absorbent materials provide effective compression and an improved environment next to a wearer's skin, which provides greater comfort and improved overall performance. Two and multi-layer compression garments are described. An outer layer may be formed with an opening having a closure and an elastic material joining the sides of the opening. This provides a first level of compression with the closure open and a second level of compression with the closure closed and also helps a user in applying the garment.