Abstract: The present invention provides for devices and methods of isolating particles. A fluidics particle isolation device is disclosed having a fluidic channel extending therethrough, wherein a segment of the fluidic channel is exposed to an asymmetric magnetic field such that when a solution containing the particles in a paramagnetic medium are passed through the magnetic field, the particles are isolated within the solution.
Type:
Grant
Filed:
September 25, 2020
Date of Patent:
May 5, 2026
Assignee:
LEVITASBIO, INC.
Inventors:
Geoffrey Facer, Kevin Travers, Andreja Jovic, Theodorus Evan De Groot
Abstract: The present invention relates generally to systems, materials, and methods utilizing magnetic levitation to affect separation and/or concentration of particulate containing samples, such as cells or biomolecules, within a medium. In some embodiments, the methods are used for the separation of a mixture of live cells and dead cells, and to isolate particle depleted medium.
Type:
Grant
Filed:
September 29, 2021
Date of Patent:
November 18, 2025
Assignee:
LEVITASBIO, INC.
Inventors:
Geoffrey Facer, Theodorus Evan de Groot, Kevin Travers, Lesley Suzanne Weaver
Abstract: Described are various embodiments of methods, devices, systems and kits for magnetic levitation-based separation of mixtures or populations of particles that include various types of particles. Some embodiments of such methods, devices, systems and kits are useful for magnetic levitation-based separation of mixtures or populations of cells that include various cell types. Some other embodiments of the described methods, devices, systems and kits are useful for magnetic levitation-based separation of mixtures or population of cellular or mixtures or population of biological molecules.
Type:
Application
Filed:
October 11, 2022
Publication date:
April 13, 2023
Applicant:
LevitasBio, Inc.
Inventors:
Kathy Lazaruk, Christopher Stevens, Kevin Travers
Abstract: Magnetic levitation particle separation systems and methods for use with multi-channel flow cells. The system may include a core for receiving and holding the flow cell, with upper and lower clamps for securing the flow cell and positioning it relative to an array of magnets. The system is configured to image particle separation in processing channels of the flow cell, and to regulate the flow cell's temperature. The core may be removable as a single unit, facilitating reconfiguration of the system.
Type:
Application
Filed:
October 7, 2022
Publication date:
April 13, 2023
Applicant:
LevitasBio, Inc.
Inventors:
Theodorus Evan de Groot, Geoff Facer, Amirreza Malekanfard, Gang Sun, Lesley Suzanne Weaver
Abstract: Described are various embodiments of methods, devices, systems and kits for magnetic levitation-based separation of mixtures or populations of particles that include various types of particles. Some embodiments of such methods, devices, systems and kits are useful for magnetic levitation-based separation of mixtures or populations of cells that include various cell types. Some other embodiments of the described methods, devices, systems and kits are useful for magnetic levitation-based separation of mixtures or population of cellular or mixtures or population of biological molecules.
Type:
Application
Filed:
October 11, 2022
Publication date:
April 13, 2023
Applicant:
LevitasBio, Inc.
Inventors:
Kathy Lazaruk, Christopher Stevens, Kevin Travers