Abstract: In a vessel, such as a flexible bag, a fluid is received and agitated using an internal fluid-agitating element driven by an external motive device and supported by a bearing, such as a roller bearing.

Abstract: A system for pumping or mixing a fluid using a rotating pumping or mixing element and various other components for use in a pumping or mixing system are disclosed.

Abstract: An apparatus detects a leak of an electrically conductive fluid from a disposable plastic bag used in mixing applications, such as during bioprocessing in a sterile environment. In one embodiment, the bag is associated with a sensor for detecting a leak from an interior compartment. The sensor may be arranged to detect either a leak internal to the at least two material layers of the bag or external to the outer layer, or both. Related methods are also disclosed.

Abstract: A vessel in which a fluid is received and agitated using an internal fluidagitating element driven by an external motive device is disclosed. In one aspect, the vessel is a bag including a first receiver for receiving and holding a fluid-agitating element at a home location. The first receiver may be in the form of an inwardly projecting post having an oversized portion for capturing the fluid-agitating element, but various other forms are disclosed. Use of this feature in completely rigid vessels where the fluid-agitating element is free of direct attachment from a first receiver having an oversized portion is also disclosed. In another aspect, the vessel or bag further includes a second receiver for receiving a portion of an external structure, such as a motive device, and aligning the vessel relative thereto. Related methods are also disclosed.

Abstract: A mixing bag for use in bioprocessing in which a fluid is received and agitated using an internal fluid-agitating element driven by an external motive device is disclosed. The bag may include an integral sparger and sensor receiver. Related methods are also disclosed.

Abstract: A system for pumping or mixing a fluid using a rotating pumping or mixing element and various other components for use in a pumping or mixing system are disclosed.

Abstract: A mixing bag for use in bioprocessing in which a fluid is received and agitated using an internal fluid-agitating element driven by an external motive device is disclosed. The bag may include an integral sparger and sensor receiver. Related methods are also disclosed.

Abstract: A system for pumping or mixing a fluid using a levitating, rotating magnetic element and various other components for use in a pumping or mixing system are disclosed. The magnetic element is placed in a vessel or container that can be positioned in close proximity to a superconducting element. The vessel or container may be sealed with the magnetic element and a product therein, with the fluid being introduced after sealing. Preferably, the vessel or container is capable of holding fluid volumes greater than 10 liters.

Abstract: Various alignment systems, devices, and related methods are for use in associated with the mixing of fluid in a vessel, such as a flexible bag, using an internal fluid-agitating element driven by an external motive device.

Abstract: A kit for assisting in the set-up of a fluid pumping or mixing system including a superconducting element capable of reaching a transition temperature during a field cooling process is disclosed. In one embodiment, the kit comprises at least one pumping or mixing element including a levitation magnet and at least one charging magnet substantially corresponding in size, shape, and magnetic field distribution to the levitation magnet. The presence of the charging magnet adjacent the superconducting element during the field cooling process enables stable levitation of the pumping or mixing element, including when in a fluid-filled vessel positioned adjacent the superconducting element.

Abstract: A system for pumping or mixing a fluid using a levitating, rotating pumping or mixing element and various other components for use in a pumping or mixing system are disclosed. The pumping or mixing element is placed in a fluid-containing vessel in close proximity to a superconducting element. A cooling source thermally linked to the superconducting element provides the necessary cooling to induce levitation in the pumping or mixing element. The superconducting element may be thermally isolated, such that the pumping or mixing element, the vessel, and any fluid contained therein are not exposed to the cold temperatures required to produce the desired superconductive effects and the resulting levitation. By using means external to the vessel to rotate and/or stabilize the pumping or mixing element levitating in the fluid, including possibly rotating the superconducting element itself or moving it relative to the vessel, the desired effective pumping or mixing action may be provided.

Abstract: A kit for assisting in the set-up of a fluid pumping or mixing system including a superconducting element capable of reaching a transition temperature during a field cooling process is disclosed. In one embodiment, the kit comprises at least one pumping or mixing element including a levitation magnet and at least one charging magnet substantially corresponding in size, shape, and magnetic field distribution to the levitation magnet. The presence of the charging magnet adjacent the superconducting element during the field cooling process enables stable levitation of the pumping or mixing element, including when in a fluid-filled vessel positioned adjacent the superconducting element.

Abstract: A system for pumping or mixing a fluid using a levitating, rotating magnetic element and various other components for use in a pumping or mixing system are disclosed. The magnetic element is placed in a vessel or container that can be positioned in close proximity to a superconducting element. The vessel or container may be sealed with the magnetic element and a product therein, with the fluid being introduced after sealing. Preferably, the vessel or container is capable of holding fluid volumes greater than 10 liters.

Abstract: A system for pumping or mixing a fluid using a levitating, rotating magnetic bearing and various other components for use in a pumping or mixing system are disclosed. The magnetic bearing is placed in a fluid-containing vessel in close proximity to a superconducting element. A separate cooling source thermally linked to the superconducting element provides the necessary cooling to induce levitation in the magnetic bearing. The superconducting element may be thermally isolated, such that the bearing, the vessel, and any fluid contained therein are not exposed to the cold temperatures required to produce the desired superconductive effects and the resulting levitation. By using means external to the vessel to rotate and/or stabilize the magnetic bearing levitating in the fluid, including possibly rotating the superconducting element itself or moving it relative to the vessel, the desired effective pumping or mixing action may be provided.

Abstract: A mixing bag usable in chemical and bioprocessing procedures that is hermetically sealed about a tube that is closed within the bag but extends out through a seal and adapted to receive a rotatable rigid rod of a predetermined shape for mixing the materials in the bag.