Patents Assigned to LIEBER INSTITUTE FOR BRAIN DEVELOPMENT
  • COMT inhibiting methods and compositions
    Patent number: 10479790
    Abstract: The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: November 19, 2019
    Assignee: LIEBER INSTITUTE FOR BRAIN DEVELOPMENT
    Inventors: James Barrow, Glen Ernst, Yifang Huang, Ingrid Price Buchler, Daniel Weinberger
  • COMT inhibiting methods and compositions
    Patent number: 10035799
    Abstract: The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: July 31, 2018
    Assignee: LIEBER INSTITUTE FOR BRAIN DEVELOPMENT
    Inventors: James Barrow, Glen Ernst, Yifang Huang, Ingrid Price Buchler, Daniel Weinberger
  • COMT inhibiting methods and compositions
    Patent number: 9951057
    Abstract: The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: April 24, 2018
    Assignee: LIEBER INSTITUTE FOR BRAIN DEVELOPMENT
    Inventors: James Barrow, Glen Ernst, Yifang Huang, Ingrid Price Buchler, Daniel Weinberger