Patents Assigned to Lieden University Medical Center (LUMC)
  • Genetic polymorphisms associated with venous thrombosis, methods of detection and uses thereof
    Patent number: 7910303
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with coronary heart disease and in particular VT and response to drug treatment. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: March 22, 2011
    Assignees: Celera Corporation, Lieden University Medical Center (LUMC)
    Inventors: Lance Bare, James J. Devlin, Frits R. Rosendaal, Pieter H. Reitsma, Irene D. Bezemer