Abstract: The present invention is directed to a 3D ultrasound-guided intraoperative brachytherapy method for the diagnosis and treatment of prostate cancer in men. The method comprises the steps of a pre-implant planning phase using 3D TRUS and semi-automated contouring, an implantation phase and a post plan verification phase for monitoring.

Abstract: A method and system, employed in combination with a three-dimensional ultrasonographic imaging system, for assisting and placing at least one medical instrument into a prostate during a percutaneous prostrate therapeutic procedure. A process means for determining the spatial relationship between three-dimensional ultrasonographic images of the prostate generated via the transrectal transducer and a reference means. In addition, the method and system assists in guiding and placement of the medical instrument into a target location in the prostate.

Abstract: The present invention provides a mounting assembly, for use with an ultrasound transducer attached to an ultrasound machine, for determining the spacial relationship between a succession of 2D image slices of a target of a subject, generated by the ultrasound machine. The mounting assembly comprises: (i) means to mount an ultrasound transducer; (ii) means to engage a surface of the subject in the proximity of the target, the means to engage a surface being moveably attached to the means to mount an ultrasound transducer; and (iii) sensing means, in communication with the means to engage a surface, to measure the movement of the means to engage a surface during acquisition of the succession of 2D image slices. Preferably, the sensing means comprises a tilt sensor and a displacement sensor.

Abstract: The present invention provides a system for the dynamic display of three-dimensional (3D) images of a target, comprising: memory means to store the plurality of time-dependent 3D image data sets; an address pointer defining an independent address of a location in the memory means of each time-dependent 3D image data set; and display means utilizing the address pointer successively to retrieve a time-dependent 3D image data set from memory and display a time-dependent 3D image corresponding to the time-dependent 3D image data set for a selected period of time. A method for dynamic display of 3D images is also provided.

Abstract: A depth-limited image processor employed in combination with a three-dimensional ultrasonographic system whereby, from a model representing at least a portion of a three-dimensional volumetric array, a user selecta a ray-depth from at least one face of the model thereby forming a “thick-plane” region of interest. All voxels within the “thick-plane” are processed successively according to a user selected imaging technique along the depth of the ray. The results of the processing are projected onto corresponding screen pixels to produce an enhanced three-dimensional image. In another embodiment, an adaptive depth-limited image processing means is employed whereby voxels are first checked against a user selected condition. voxels meeting this condition are then processed as above to produce an enhanced three-dimensional image.

Abstract: A system and process are provided for performing percutaneous biopsy within a breast using three-dimension ultrasonography and including a breast positioning device, a breast immobilization device, an ultrasonic imaging device, a biopsy instrument positioning device, the breast immobilization device and the three-dimensional ultrasonographic imaging device being positioned in a known relationship to each other, the breast immobilization device being employed to immobilize the breast and a lesion contained therein for imaging by the three-dimensional ultrasonic imaging device, and the three-dimensional ultrasonic imaging device being employed to assist an operator in positioning the biopsy instrument positioning device relative to the lesion and guiding a biopsy instrument percutaneously to the lesion.

Abstract: The present invention provides a semi-automated method for three-dimensional ultrasound for constructing and displaying 3-D ultrasound images of luminal surfaces of blood vessels. The method comprises acquiring a 3-D ultrasound image of a target vessel and segmenting the luminal surfaces acquired from the 3-D ultrasound image of the target vessel to generate a 3-D ultrasound image of the lumen of the target vessel, wherein an inflating balloon model is used for segmenting the luminal surfaces of the target vessel. The method is useful for diagnostic assessment of bodily vessels as well as provides for therapy planning and as a prognostic indicator.

Abstract: A three-dimensional ultrasound imaging system includes an ultrasound probe to direct ultrasound waves to and to receive reflected ultrasound waves from a target volume of a subject under examination. The ultrasound probe is swept over the target volume along a linear scanning path and the reflected ultrasound waves are conveyed to a computer wherein successive two-dimensional images of the target volume are digitized. The digitized two-dimensional images can be used to generate a three-dimensional image with virtually no delay. A user interface allows a user to manipulate the displayed image. Specifically, the entire displayed image may be rotated about an arbitrary axis, a surface of the displayed image may be translated to provide different cross-sectional views of the image and a selected surface of the displayed image may be rotated about an arbitrary axis. All of these manipulations can be achieved via a single graphical input device such as a mouse connected to the computer.