Abstract: The present invention relates to novel compounds of the formula (I) that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other tauopathies using Positron Emission Tomography (PET) Imaging.
Type:
Grant
Filed:
July 21, 2017
Date of Patent:
December 15, 2020
Assignees:
AC IMMUNE S.A., LIFE MOLECULAR IMAGING SA
Inventors:
Heiko Kroth, Jérôme Molette, Hanno Schieferstein, Andre Müller, Heribert Schmitt-Willich, Mathias Berndt, Felix Oden
Abstract: The present invention relates to novel compounds of the formula (II) that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other tauopathies using Positron Emission Tomography (PET) Imaging.
Type:
Grant
Filed:
July 21, 2017
Date of Patent:
November 17, 2020
Assignees:
AC IMMUNE S.A., LIFE MOLECULAR IMAGING SA
Inventors:
Heiko Kroth, Jérôme Molette, Vincent Darmency, Hanno Schieferstein, Andre Müller, Heribert Schmitt-Willich, Mathias Berndt, Felix Oden, Emanuele Gabellieri
Abstract: The present invention relates to novel compounds that can be employed in the diagnosis, treatment, alleviation or prevention of a group of disorders and abnormalities associated with amyloid proteins and amyloid-like proteins, such as Alzheimer's disease. Precursors for the preparation of the compounds according to the present invention are also provided.
Type:
Grant
Filed:
January 21, 2015
Date of Patent:
May 26, 2020
Assignees:
AC IMMUNE SA, LIFE MOLECULAR IMAGING SA
Inventors:
Heiko Kroth, Sreenivasachary Nampally, Jér{hacek over (o)}me Molette, Emanuele Gabellieri, Pascal André René Benderitter, Wolfgang Froestl, Hanno Schieferstein, Andre Mueller, Heribert Schmitt-Willich, Mathias Berndt