Abstract: Various examples are provided for water purification systems that employ filters, and more particularly to water purification systems that extend the life of such filters. In one example, the water purification system includes a valve that in an energized position allows the flow of unfiltered water through a filter assembly containing filters. A monitor is provided to detect whether the faucet has been moved to the closed position. In the event no movement of the faucet from the closed position is detected within a predefined time interval, then the valve is de-energized causing water flow to bypass the filter assembly, thus extending filter life. In another example, the water purification system provides a flow path having a straight-line geometry to provide for quieter water flow and reduces pressure drop.

Abstract: A network node stores connection data required for remote devices to connect with it and to share content data with it. The network node shares the connection data with other network nodes that are capable of communicating with the remote device, and retrieves connection data for a remote device from another network node if the connection data is not stored in the first node. The network node also communicates with a remote server to retrieve the connection data if it is not present in one of the other network nodes. The network node securely communicates content data received from the remote devices to a remote data store.

Abstract: Disclosed herein is a method for assessing the probability of embryo implantation success during the in vitro fertilization process. A method of the disclosure can predict embryo implantation success based on, for example, the amount of specific metabolites present in embryo conditioned culture media.

Abstract: A facility providing systems and methods for discovering novel features to use in machine learning techniques. The facility receives, for a number of subjects, one or more sets of data representative of some output or condition of the subject over a period of time or capturing some physical aspect of the subject. The facility then extracts or computes values from the data and applies one or more feature generators to the extracted values. Based on the outputs of the feature generators, the facility identifies novel feature generators for use in at least one machine learning process and further mutates the novel feature generators, which can then be applied to the received data to identify additional novel feature generators.

Abstract: Biochips coupling system and devices refers to biochip coupling devices, biochips, and coupling systems comprising biochip coupling devices and biochips. In some embodiments, a coupling device is integrated with a reusable station that comprises a pneumatic system for which a biochip having at least one microfluidic channel can be inserted therein. In some embodiments, a coupling device can be integrated with other apparatuses with pneumatic systems to which biochips can be coupled. In some embodiments, systems, devices, and biochips described herein are used for biological protocols, for example, vitrification (cryopreservation) and warming (thawing) of embryos. The systems, devices, and biochips described herein can be configured for automated or manual use.

Abstract: Disclosed herein are microfluidic devices and methods to deliver concentration gradients to biological material such as oocytes and embryos for the purpose of cryopreparation, cryopreservation, or thawing. Cryopreservation methods, such as vitrification, involve the use of cryoprotectants to reduce formation of damaging ice crystals in cells during freezing. Microfluidic devices and methods described herein improve cell viability and efficiency during handling and cryopreservation of biological materials.

Abstract: The techniques described herein may provide for an evidence-based, clinical practice guideline-driven, patient communication system. A user (e.g., a patient, a client, etc.) may interact with, or use, a patient communication system for improved healthcare according to one or more aspects. The patient communication system may credibly categorize user inputs into injury patterns (e.g., correlated to healthcare industry established clinical practice guidelines). For instance, an evidence-based, clinical practice guideline-driven, patient communication system may utilize a library of extensive and credible healthcare information (e.g., reviewed by a credible body established by the healthcare industry). Such information may include physical therapy videos, recovery strategies, workplace group or client-group healthcare information, etc. The patient communication system may generate (e.g.

Abstract: Disclosed herein is a method for assessing the probability of embryo implantation success during the in vitro fertilization process. A method of the disclosure can predict embryo implantation success based on, for example, the amount of specific metabolites present in embryo conditioned culture media.

Abstract: A single-channel Long Range (LoRa) receiver device. The device may comprise a communication component comprising a receiver spreading factor (SF), configured to accept LoRa signals. LoRa signals each comprise a transmitter SF. The communication component is only able to receive a LoRa signal if the receiver SF matches the transmitter SF. The device may change its receiver SF and detect LoRa signals. The device may then analyze a LoRa signal if the transmitter SF matches the receiver SF. The device may then synchronize the communication component to the LoRa signal, process the LoRa signal, and repeat changing, detecting, analyzing, and synchronizing until all LoRa signals in range are processed.

Abstract: Disclosed herein are microfluidic devices and methods to deliver concentration gradients to biological material such as oocytes and embryos for the purpose of cryopreparation, cryopreservation, or thawing. Cryopreservation methods, such as vitrification, involve the use of cryoprotectants to reduce formation of damaging ice crystals in cells during freezing. Microfluidic devices and methods described herein improve cell viability and efficiency during handling and cryopreservation of biological materials.

Abstract: A network node is adapted to wirelessly receive content data from remote wireless devices if they have been provisioned to the network node via provisioning data. The network node includes a memory for storing first provisioning data, a transceiver adapted to transmit a portion of the first provisioning data for receipt and storage by a second node, receive a portion of second provisioning data stored in the second node, communicate with a remote cloud based source of provisioning data, transmit content data communicated to the first node by a wireless device to a remote data store, and a programmable processor. The processor determines whether a detected device has or has not been formerly provisioned with the first node. If the detected device has not been formerly provisioned with the first node, and if provisioning data for the detected device is not available in the first or the second provisioning data, provisioning data for the detected device is obtained from the remote cloud based source.

Abstract: A gateway has a transceiver for communicating with Bluetooth vitals devices (BVDs) and a processor and program instructions. The gateway receives and stores pairing keys from one or more of the BVDs for provisioning the BVDs to the gateway, receives vital sign information from the BVDs, stores the pairing keys in a remote trusted server, and communicates with other gateways in the environment. The gateway also retrieves pairing keys for unprovisioned BVDs from either another gateway or the remote trusted server, and creates a remote private network for secure communications among two or more of the gateway, the remote server, an electronic health records store, caregivers, physicians, or a personalized data service.

Abstract: A device for organizing and tracking medication. The device includes compartments to contain medication, and each compartment includes an access door. A sensor element can detect if the device is moved, if the access door is opened and/or closed, and/or if medications have been placed into or removed from a compartment. A processor and/or external computing system provides alarms if medications is not properly taken, a filling service for stuffing the compartments and an administration service to verify the medications are properly taken.

Abstract: A method for factory calibration of a sensor of a CGM system is disclosed. A processor receives an enzyme membrane thickness after each dip of a working wire according to first parameters. The processor receives a glucose limiting membrane thickness after each dip of the working wire according to second parameters. The processor determines a working wire diameter, and includes the membrane thicknesses. The processor in communication with the CGM system, automatically generates a correlation between the first and the second parameters to at least one of a factory sensitivity and a drift profile. The drift profile predicts a sensitivity of the sensor over time. The processor associates the at least one of the factory sensitivity or the drift profile with the sensor. The sensor outputs a glucose reading during in-vivo use based on the at least one of the factory sensitivity or the drift profile.

Abstract: A pressure-sensing device includes a device frame, a flexible membrane, a pressure sensor, and device electronics. The device frame includes a base surface that rests on a supporting structure and a frame attachment region located opposite to the base surface such that the frame attachment region is raised from the supporting structure when the base surface is resting on the supporting structure. The device frame also includes a seating surface. The flexible membrane is attached to the frame attachment region such that the device frame and the flexible membrane enclose a pressure chamber. The seating surface extends outward around the flexible membrane and the flexible membrane protrudes above the seating surface. The pressure sensor is configured to generate a pressure signal. The device electronics are configured to determine the pressure in the pressure chamber based on the pressure signal.

Abstract: Ultrathin absorbent hygienic pads comprising a top layer, a middle absorbent layer, and a bottom layer and comprising one or more channels anchored from the top layer through the middle absorbent layer and into the bottom layer are provided. The ultrathin absorbent hygienic pads provided can be used to absorb bodily fluids.

Abstract: The present disclosure facilitates the evaluation of wide-band phase gradient information of the heart tissue to assess, e.g., the presence of heart ischemic heart disease. Notably, the present disclosure provides an improved and efficient method to identify and risk stratify coronary stenosis of the heart using a high resolution and wide-band cardiac gradient obtained from the patient. The patient data are derived from the cardiac gradient waveforms across one or more leads, in some embodiments, resulting in high-dimensional data and long cardiac gradient records that exhibit complex nonlinear variability. Space-time analysis, via numeric wavelet operators, is used to study the morphology of the cardiac gradient data as a phase space dataset by extracting dynamical and geometrical properties from the phase space dataset.

Abstract: The present disclosure facilitates capture of biosignal such as biopotential signals in microvolts, or sub-microvolts, resolutions that are at, or significantly below, the noise-floor of conventional electrocardiographic and biosignal acquisition instruments. In some embodiments, the exemplified system disclosed herein facilitates the acquisition and recording of wide-band phase gradient signals (e.g., wide-band cardiac phase gradient signals, wide-band cerebral phase gradient signals) that are simultaneously sampled, in some embodiments, having a temporal skew less than about 1 ?s, and in other embodiments, having a temporal skew not more than about 10 femtoseconds. Notably, the exemplified system minimizes non-linear distortions (e.g., those that can be introduced via certain filters) in the acquired wide-band phase gradient signal so as to not affect the information therein.

Abstract: Systems, methods, and apparatuses are provided for multi-channel communication based real-time geolocation of an object entity. The system is structured for dynamic location of an object and real-time notification transmission to an object owner. The system receives a first communication message associated with a first identification code from a first user device, and determines an object entity associated with the first identification code and the object tag component, based on analyzing the first communication message. Subsequently, typically, the system constructs an object location interface associated with the determined object entity, wherein the object attribute interface comprises a location display component associated with the captured geolocation parameter associated with the first user device. The system initiates presentation of the object location interface at the owner device associated with the object entity.