Abstract: Among other things, the present disclosure provides technologies for efficient and effective identification of ETaGs, for example, from fungi genomes. In some embodiments, provided technologies are particularly useful for identifying mammalian targets of biosynthetic products of fungi. In some embodiments, provided technologies are particularly useful for identifying and/or prioritizing human targets for drug development. In some embodiments, provided technologies are particularly useful for developing modulators for human targets based on biosynthetic products of fungi.
Type:
Grant
Filed:
July 13, 2023
Date of Patent:
March 4, 2025
Assignee:
LifeMine Therapeutics, Inc.
Inventors:
John Baxter Biggins, Brian Roger Bowman, Gregory L. Verdine
Abstract: Among other things, the present disclosure provides technologies for efficient and effective identification of ETaGs, for example, from fungi genomes. In some embodiments, provided technologies are particularly useful for identifying mammalian targets of biosynthetic products of fungi. In some embodiments, provided technologies are particularly useful for identifying and/or prioritizing human targets for drug development. In some embodiments, provided technologies are particularly useful for developing modulators for human targets based on biosynthetic products of fungi.
Type:
Grant
Filed:
September 14, 2018
Date of Patent:
September 5, 2023
Assignee:
LIFEMINE THERAPEUTICS, INC.
Inventors:
John Baxter Biggins, Brian Roger Bowman, Gregory L. Verdine