Abstract: Assemblies are provided for collecting a sample from a mouth using an integrated sample collection tip. A sample collection assembly includes a sample collection body configured for being placed within the mouth, wherein the sample collection body includes a bore and one or more pores. The sample collection assembly further includes a conduit that disposed within the bore of the sample collection body and that is in fluid communication with the one or more pores. The conduit is bonded within the bore. The sample collection assembly can further include a hand piece that has a tip on which the sample collection body is mounted, and through which the conduit can extend. The pores can include a plurality of micropores. The sample collection body can be hydrophobic, and a hydrophilic surfactant can be disposed on the outer surface of the sample collection body.

Abstract: In this disclosure, novel caanabinol-based tracers suitable for use in immunoassays that detect cannabinoids in a biological sample are disclosed. These cannabinol-based tracers are particularly useful in a continuous flow displacement immunoassay. The disclosure also describes the processes for synthesizing the novel tracers, and the application of these tracers in fluorescence immunoassays for detecting and quantifying cannabinoids in biological samples.

Abstract: This invention relates to novel tracers and their synthesis and use in an immunoassay for the detection of controlled drugs such as amphetamine (APM), methamphetamine (MAPM) and their derivatives, in a biological or aqueous sample. In particular, this invention provides methods for synthesizing novel tracers in which a non-controlled substance is both the starting material in tracer synthesis and the binding site on the resulting novel tracer for the antibody, thereby eliminating the necessity of using controlled substances as starting materials. In addition, the novel tracers of the present invention can be used as an analyte analog in an immunoassay, such as a continuous flow displacement immunoassay. It was unexpectedly discovered that the novel tracers of the present invention substantially improve the performance of the continuous flow displacement immunoassay as compared with conventionally designed tracers.

Abstract: In this disclosure, novel caanabinol-based tracers suitable for use in immunoassays that detect cannabinoids in a biological sample are disclosed. These cannabinol-based tracers are particularly useful in a continuous flow displacement immunoassay. The disclosure also describes the processes for synthesizing the novel tracers, and the application of these tracers in fluorescence immunoassays for detecting and quantifying cannabinoids in biological samples.

Abstract: A device for measuring, concurrently from the same sample solution, the pH and presence or quantity of an analyte in the solution. The pH and analyte measuring sections of the invention are contained within the same holding structure.

Abstract: A method and device for automatic or semi-automatic collection of saliva has a mouthpiece on a wand. The wand is connected to an interface section via a flexible conduit. Saliva is transported by aspiration into the device. Bulk air is removed and saliva is collected in a collection chamber. For collection of volatile components, air flow, vacuum, conduit diameter and length, and collection times are controlled and limited, to reduce loss of volatile components.