Abstract: Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.
Type:
Grant
Filed:
October 23, 2019
Date of Patent:
October 26, 2021
Assignee:
LifeRaft Biosciences, Inc.
Inventors:
R. Martin Emanuele, Mannarsamy Balasubramanian, Stewart V. Smith
Abstract: Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.
Type:
Application
Filed:
October 23, 2019
Publication date:
February 20, 2020
Applicant:
LifeRaft Biosciences, Inc.
Inventors:
R. Martin Emanuele, Mannarsamy BALASUBRAMANIAN, Stewart V. SMITH
Abstract: Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.
Type:
Grant
Filed:
July 11, 2016
Date of Patent:
December 10, 2019
Assignee:
LifeRaft Biosciences, Inc.
Inventors:
R. Martin Emanuele, Mannarsamy Balasubramanian, Stewart V. Smith