Abstract: A physiologic monitoring system and corresponding methods provide rapid and detailed analysis of data for one or more physiologic parameters to achieve a quick and accurate medical diagnosis. An ambulatory physiological monitoring unit acquires physiologic data, automatically analyzes it to detect an event, and transmits information regarding the event and physiologic data associated with the event across a communications network to a monitoring center, where the event information is analyzed and triaged. The monitoring center can also perform a retrospective analysis based on the physiological data associated with the event to provide an in-depth analysis of the detected event and an accurate diagnosis. The monitoring center can also request additional or different physiological data to refine the analysis. As a result, the physiological monitoring system and corresponding methods can ensure that timely and appropriate intervention is taken to reduce a patient's discomfort, pain, injury, or risk of death.