Patents Assigned to Ligand Pharmacueticals Incorparated
  • Process for the preparation of 1,2-dihydroquinolines
    Patent number: 6180794
    Abstract: A method for preparing 1,2-dihydroquinolines that is more flexible than the Skraup reaction is provided. The method comprises treating an ortho-alkenyl aniline with a ketone in the presence of a Lewis acid. Novel intermediates and products of this method useful as steroid receptor modulators, as well as pharmaceutical compositions and methods of use thereof are also claimed.
    Type: Grant
    Filed: October 15, 1999
    Date of Patent: January 30, 2001
    Assignee: Ligand Pharmacueticals Incorparated
    Inventors: James P. Edwards, Todd K. Jones, Josef D. Riggenberg, Erick M. Carreira