Abstract: The present invention provides a method for evaluating the efficacy of an EGFR-TKI treatment to a subject, comprising identifying the V384D mutation in said subject. By identifying said mutation, the efficacy of the EGFR-TKI treatment and the progression-free survival of said subject after treatment can be estimated.
Abstract: The present invention provides a primer set and a kit containing same for analyzing a sequence of an MLH1 DNA, an MLH1 mRNA, and/or a cDNA sequence derived from said MLH1 mRNA of a subject to identify a V384 alteration of an MLH1 gene encoded protein.
Type:
Grant
Filed:
September 16, 2015
Date of Patent:
August 13, 2019
Assignee:
LIHPAO LIFE SCIENCE CORP.
Inventors:
Chih-Hao Chen, Meng-Ju Lee, Chia-Lin Wu, Yu-Wei Liu
Abstract: The present invention provides a method for evaluating the efficacy of an EGFR-TKI treatment to a subject, comprising identifying the V384D mutation in said subject. By identifying said mutation, the efficacy of the EGFR-TKI treatment and the progression-free survival of said subject after treatment can be estimated.
Abstract: The present invention provides a method for evaluating the efficacy of an EGFR-TKI treatment to a subject, comprising identifying the V384D mutation in said subject. By identifying said mutation, the efficacy of the EGFR-TKI treatment and the progression-free survival of said subject after treatment can be estimated.
Abstract: The present invention provides a primer set and a kit containing same for analyzing a sequence of an MLH1 DNA, an MLH1 mRNA, and/or a cDNA sequence derived from said MLH1 mRNA of a subject to identify a V384 alteration of an MLH1 gene encoded protein.
Type:
Application
Filed:
September 16, 2015
Publication date:
October 12, 2017
Applicant:
Lihpao Life Science Corp.
Inventors:
CHIH-HAO CHEN, MENG-JU LEE, CHIA-LIN WU, YU-WEI LIU
Abstract: The present invention provides a method for evaluating the efficacy of an EGFR-TKI treatment to an object, comprising identifying the V384D mutation in said object. By identifying said mutation, the efficacy of the EGFR-TKI treatment and the progression-free survival of said object after treatment can be estimated.