Patents Assigned to LIMITED LIABILITY COMPANY "CARDIOSYSTEMPHARMA" (LLC "CSP")
  • Publication number: 20200230171
    Abstract: This invention relates to medicine, more specifically, to cardiac surgery, and may be used for protecting the heart from ischemia when administering cardioplegia in normothermia or hypothermia. The general-purpose cardioplegic solution contains pharmaceutically acceptable potassium ions; magnesium ions; a base and an acid providing a pH buffer in a range of 7.1-8.9; a diuretic providing osmolality in a range of 275-460 mOsmol/kg. Said solution is used for cardiac protection in cardiopulmonary bypass, as well as for achieving asystole and maintaining the achieved asystole. The procedure for administering the general-purpose cardioplegic solution involves maintaining the achieved asystole by decreasing the flow rate of starting components of said solution relative to the flow rate of autoblood thus decreasing the solution to autoblood ratio.
    Type: Application
    Filed: April 8, 2020
    Publication date: July 23, 2020
    Applicant: LIMITED LIABILITY COMPANY "CARDIOSYSTEMPHARMA" (LLC "CSP")
    Inventor: Valentin Evgenevich VOLGUSHEV
  • Publication number: 20170143760
    Abstract: This invention relates to medicine, more specifically, to cardiac surgery, and may be used for protecting the heart from ischemia when administering cardioplegia in normothermia or hypothermia. The general-purpose cardioplegic solution contains pharmaceutically acceptable potassium ions; magnesium ions; a base and an acid providing a pH buffer in a range of 7.1-8.9; a diuretic providing osmolality in a range of 275-460 mOsmol/kg. Said solution is used for cardiac protection in cardiopulmonary bypass, as well as for achieving asystole and maintaining the achieved asystole. The procedure for administering the general-purpose cardioplegic solution involves maintaining the achieved asystole by decreasing the flow rate of starting components of said solution relative to the flow rate of autoblood thus decreasing the solution to autoblood ratio.
    Type: Application
    Filed: June 5, 2015
    Publication date: May 25, 2017
    Applicant: LIMITED LIABILITY COMPANY "CARDIOSYSTEMPHARMA" (LLC "CSP")
    Inventor: Valentin Evgenevich VOLGUSHEV