Patents Assigned to Limited Partnership No. 1
  • Novel oral dosage form for carvedilol
    Publication number: 20040220250
    Abstract: The present invention discloses a matrix formulation containing carvedilol.
    Type: Application
    Filed: January 16, 2003
    Publication date: November 4, 2004
    Applicants: Boehringer Mannhein Pharmaceutical Corporation, SmithKline Beckman Corporation, Limited Partnership No. 1
    Inventor: Choon K. Oh
  • Method of treatment for decreasing mortality resulting from congestive heart failure
    Publication number: 20030105138
    Abstract: A method of treatment using a compound of Formula I: 1
    Type: Application
    Filed: December 19, 2002
    Publication date: June 5, 2003
    Applicant: Boehringer Mannheim Pharmaceuticals Corporation- SmithKline Beecham Corp. Limited Partnership No. 1
    Inventors: Mary Ann Lukas-Laskey, Robert Ruffolo, Neil Howard Shusterman, Gisbert Sponer, Klaus Strein
  • Method for treating Alzheimer's disease
    Patent number: 6358990
    Abstract: A method of treating amyloid diseases by administering a compound of Formula I: wherein: R7-R13 are independently —H or —OH; and A is H, —OH, or a moiety of Formula II:  wherein: R1 is hydrogen, lower alkanoyl of up to 6 carbon atoms or aroyl selected from benzoyl and naphthoyl; R2 is hydrogen, lower alkyl of up to 6 carbon atoms or arylalkyl selected from benzyl, phenylethyl and phenylpropyl; R3 is hydrogen or lower alkyl of up to 6 carbon atoms; R4 is hydrogen or lower alkyl of up to 6 carbon atoms, or when X is oxygen, R4 together with R5 can represent —CH2—O—; X is a valency bond, —CH2, oxygen or sulfur; Ar is selected from phenyl, naphthyl, indanyl and tetrahydronaphthyl; R5 and R6 are individually selected from hydrogen, fluorine, chlorine, bromine, hydroxyl, lower alkyl of up to 6 carbon atoms, a —CONH2— group, lower alkoxy of up to 6 carbon atoms, benzyloxy, lower alkylthio of up to 6 carbon atoms,
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: March 19, 2002
    Assignees: Boehringer Mannheim Pharmaceuticals Corp., SmithKline Beckman Corp. Limited Partnership No. 1
    Inventors: David Robert Howlett, Davina Elizabeth Mitchell
  • Method for inhibiting the expression of Fas
    Patent number: 6096777
    Abstract: The present invention relates to a new method of treatment using compounds which are dual non-selective beta-adrenoceptor and alpha-1-adrenoceptor antagonists, in particularly the carbazolyl-(4)-oxypropanolainine compounds of Formula 1, as defined herein, for inhibiting the expression of Fas, a cell surface protein.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: August 1, 2000
    Assignees: Boehringer Mannheim Pharmaceuticals Corporation, SmithKline Bechman Corporation Limited Partnership No. 1
    Inventors: Giora Zeev Feuerstein, Tian-Li Yue
  • Use of carbazole compounds for the treatment of congestive heart failure
    Patent number: 5902821
    Abstract: A method of treatment using carvedilol is disclosed, wherein the carvedilol decreases the mortality caused by congestive heart failure in patients. The patients are titrated with low amounts of carvedilol, with the initial titration dosage being only 10 to 30% of the daily maintenance dose.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: May 11, 1999
    Assignee: Boehringer Mannheim Pharmaceuticals Corporation Smith Kline Corporation Limited Partnership No. 1
    Inventors: Mary Ann Lukas-Laskey, Robert Ruffolo, Jr., Neil Shusterman, Gisbert Sponer, Klaus Strein