Abstract: A system for making multi-site skin tests primarily for use by allergists making use of a multi-head applicator and a matching multi-well dipwell tray. The applicator has an elongated handle with arms extending transversely from opposite sides having downwardly extending legs terminating in multi-pointed ends or heads capable of picking up and retaining small quantities of liquid skin-testing substances. The multi-point ends or heads occupy the same plane and are arrayed in a pattern suited for simultaneously making multi-site skin tests. The applicator cooperates with a multi-well dipwell tray with a plurality of dipwells arrayed in patterns which match the pattern in which the multi-pointed ends or heads on the cooperating applicator are arrayed. The individual dipwells have a capacity to hold quantities of skin testing substances or medicaments equaling many times the volume of a single dose or increment that is picked up by one of the multi-pointed ends or heads on an applicator.