Abstract: The present invention pertains to a device (1) for the treatment of, treatment of complications arising from, and/or preventing respiratory disorders caused by bacterial, viral, protozoal, fungal and/or microbial infections, preferably for the treatment of complications arising from cystic fibrosis (CF), including a positive airway pressure device (2) for providing a breathing gas under a positive pressure to a patient interface (20), a source of nitric oxide (3) for providing gaseous nitric oxide, a gas injector (4) for injecting nitric oxide provided by the source of nitric oxide (3) into the breathing gas provided by the positive airway pressure device (2) under pressure, a flow rate sensor (5) for sensing the flow rate of the breathing gas provided to the patient interface (20) under positive airway pressure, and a controller (6) programmed for controlling the gas injector (4) for injecting the nitric oxide into the breathing gas provided by the positive airway pressure device (2) when a flow rate detecte