Abstract: The present invention provides a pharmaceutical composition for preventing and/or treating a disease characterized by fibrosis of a cell or a tissue, the pharmaceutical composition comprising a compound represented by formula 1 or a salt thereof, and a pharmaceutically acceptable carrier.
Type:
Grant
Filed:
January 30, 2020
Date of Patent:
November 12, 2024
Assignees:
SCIENCE FARM LTD., LINK GENOMICS, INC.
Inventors:
Lin Kurahara, Hironobu Ihn, Masami Otsuka
Abstract: The present invention provides a pharmaceutical composition for preventing and/or treating a disease characterized by fibrosis of a cell or a tissue, the pharmaceutical composition comprising a compound represented by formula 1 or a salt thereof, and a pharmaceutically acceptable carrier.
Type:
Application
Filed:
January 30, 2020
Publication date:
March 31, 2022
Applicants:
SCIENCE FARM LTD., LINK GENOMICS, INC.
Inventors:
Lin KURAHARA, Hironobu IHN, Masami OTSUKA
Abstract: The existent therapeutic drugs for CNV are merely pharmaceuticals for a symptomatic therapy, and therapeutic drugs for radical cure are strongly demanded. Also, a therapeutic drug for Dry AMD does not exist, and therapeutic drugs for radical cure are strongly demanded. The present invention provides a prophylactic and/or therapeutic agent for choroidal neovascularization, containing a compound having an activity of suppressing epithelial-mesenchymal transition in retinal pigment epithelial cells, as an active ingredient. Also, the present invention provides a drusen suppressor comprising a compound having an activity of suppressing epithelial-mesenchymal transition in retinal pigment epithelial cells, as an active ingredient.
Type:
Grant
Filed:
December 16, 2016
Date of Patent:
September 1, 2020
Assignees:
LINK GENOMICS, INC., ROHTO Pharmaceutical Co., Ltd.
Abstract: The present invention provides a prophylactic or therapeutic agent for various malignant tumors, including currently intractable solid tumors, which contains an antibody having the ability to bind to human LAT1/CD98 and inducing antibody-dependent cellular cytotoxicity specifically against cancer cells as an active ingredient.
Abstract: The present invention provides a prophylactic or therapeutic agent for various malignant tumors, including currently intractable solid tumors, which contains a novel antibody having the ability to bind to human LAT1/CD98 and inducing antibody-dependent cellular cytotoxicity specifically against cancer cells as an active ingredient.