Abstract: The present invention relates to novel azetidinone-containing compounds having a novel side-chain which is attached to the aryl ring at C4 via a C—C bond and comprises a 3,3-disubstituted oxetane ring and a polar group A, and which are useful in the treatment and prevention of atherosclerosis and for the reduction of cholesterol levels.
Type:
Grant
Filed:
March 5, 2010
Date of Patent:
December 15, 2015
Assignee:
Lipideon Biotechnology AG
Inventors:
Thomas Fessard, Dong-Bo Li, Damien Barbaras, Susanne Wolfrum, Erick Carreira
Abstract: The present invention relates to novel azetidinone-containing compounds having a novel side-chain which is attached to the aryl ring at C4 via a C—C bond and comprises a 3,3-disubstituted oxetane ring and a polar group A, and which are useful in the treatment and prevention of atherosclerosis and for the reduction of cholesterol levels.
Type:
Application
Filed:
March 5, 2010
Publication date:
March 15, 2012
Applicant:
LIPIDEON BIOTECHNOLOGY AG
Inventors:
Thomas Fessard, Dong-Bo Li, Damien Barbaras, Susanne Wolfrum, Erick Carreira
Abstract: The present invention relates to novel hypocholesterolemic compounds of formula (I) useful in the treatment and prevention of atherosclerosis and for the reduction of cholesterol levels as well as to pharmaceutical compositions comprising said compounds alone or in combination with other active agents.
Type:
Grant
Filed:
September 15, 2004
Date of Patent:
June 9, 2009
Assignee:
Lipideon Biotechnology AG
Inventors:
Erick Carreira, Helmut Hauser, Lisbet Kvaerno, Tobias Ritter, Moritz Werder