Patents Assigned to Lipogel
  • Patent number: 6656497
    Abstract: The invention concerns liposome vectors, in powder form, of active principles, and more particularly active principles sensitive to digestive and/or plasmatic degradation, such as proteins, and their application as medicine. Said liposome vectors of active principles consist of a powder composition essentially constituted of unilamellar liposomes comprising an external lipid phase consisting of class 4 lipids (phospholipids), optionally associated with class 2 substances, class 3 substances and/or class 5 substances and an internal aqueous nucleus consisting of a mixture M of at least two different non-polymerisable gelling agents (G1 and G2) whereof the gel-sol phase transition is not less than 37° C.
    Type: Grant
    Filed: February 17, 2000
    Date of Patent: December 2, 2003
    Assignee: Lipogel
    Inventor: Jean-Pierre Salles
  • Patent number: 6331315
    Abstract: The invention concerns powder compositions of stabilised unilamellar liposomes, comprising at least an external lipid phase and a internal aqueous polar nucleus gelled at room temperature, the method for preparing them and their applications as nutritional additives and in pharmaceutical compositions to be orally administered (with action against lipemia). Said compositions essentially consist of unilamellar liposomes comprising an external lipid phase consisting of class 4 lipids (phospholipids) and an internal aqueous nucleus consisting essentially of a mixture M of at least two different non-polymerisable gelling agents (G1 and G2) whereof the gel-sol phase transition point is not less than 37° C.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: December 18, 2001
    Assignee: Lipogel
    Inventor: Jean-Pierre Salles
  • Patent number: 6221387
    Abstract: Microspheres comprising a gelified polar core which is optionally surrounded by concentric and alternating superimposed n lipidic bilayers or n aqueous liquid layers and n gelified polar layers, n being an integer. The microspheres of the invention are obtainable by delipidation of liposomes designated as liposomes having a gelified polar core, of the type comprising at least one outer lipidic bilayer and at least one inner polar aqueous phase containing a gelified substance.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: April 24, 2001
    Assignee: Lipogel
    Inventors: Jacques Hauton, Jean-Pierre Salles
  • Patent number: 5945120
    Abstract: Microspheres comprising a gelified polar core which is optionally surrounded by concentric and alternating superimposed n lipidic bilayers or n aqueous liquid layers and n gelified polar layers, n being an integer. The microspheres of the invention are obtainable by delipidation of liposomes designated as liposomes having a gelified polar core, of the type comprising at least one outer lipidic bilayer and at least one inner polar aqueous phase containing a gelified substance.
    Type: Grant
    Filed: December 13, 1996
    Date of Patent: August 31, 1999
    Assignee: Lipogel
    Inventors: Jacques Hauton, deceased, Jean-Pierre Salles