Patents Assigned to Lipoxen Technologies Incorporated
  • Use of histones for therapeutic purposes
    Patent number: 8962562
    Abstract: The invention relates to the use of at least one human recombinant histone, especially at least one histone H1 subtype, and/or a therapeutic histone fraction as a basis for the treatment of thrombocytopenia.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: February 24, 2015
    Assignee: Lipoxen Technologies Incorporated
    Inventors: Reiner Class, Michael Zeppezauer
  • Activated sialic acid derivatives for protein derivatisation and conjugation
    Patent number: 8952141
    Abstract: Derivatives of PSAs are synthesised, in which a reducing and/or non-reducing end terminal sialic acid unit is transformed into a N-hydroxysuccinimide (NHS) group. The derivatives may be reacted with substrates, for instance substrates containing amine or hydrazine groups, to form non-cross-linked/crosslinked polysialylated compounds. The substrates may, for instance, be therapeutically useful drugs, peptides or proteins or drug delivery systems.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: February 10, 2015
    Assignee: Lipoxen Technologies Incorporated
    Inventors: Sanjay Jain, Ioannis Papaioannou, Smita Thobhani