Abstract: The invention is directed to using of the relative value of the gene expression level of the gene for ADIPOQ and/or of a gene, the expression of which has linear statistical correlation with that of the ADIPOQ gene, in the prognosis or the diagnosis of a type II diabetes mellitus disease in a test subject. Also disclosed is a method for prognosing and/or diagnosing a type II diabetes mellitus disease for classification of a subject into risk groups, wherein the gene expression level of the ADIPOQ gene and/or of a gene, the expression of which has linear statistical correlation with that of the ADIPOQ gene, is determined and the subject is subsequently classified into risk groups, taking said gene expression level into account.
Type:
Grant
Filed:
November 19, 2018
Date of Patent:
January 21, 2025
Assignee:
LIPOZYT MARKER UG
Inventors:
Uwe Jensen, Wolfgang Hierneis, Markus Klemke, Helge Wilhelm Thies
Abstract: The invention relates to a method for the prognosis of adiposity and the prognosis and/or diagnosis of a disease selected from the group consisting of diabetes, cardiovascular diseases and metabolic syndrome
Abstract: The invention relates to the use of the relative value of the gene expression level of the IL-6 gene in the prognosis or the diagnosis of a type II diabetes mellitus disease in a subject. It further relates to a method for prognosing and/or diagnosing a type II diabetes mellitus disease for classification of a subject into risk groups, wherein the gene expression level of the IL-6 gene is determined and the subject is subsequently classified into risk groups, taking said gene expression level into account.
Type:
Application
Filed:
November 19, 2018
Publication date:
December 3, 2020
Applicant:
Lipozyt Marker UG
Inventors:
Uwe JENSEN, Wolfgang HIERNEIS, Markus KLEMKE, Helge Wilhelm THIES
Abstract: The invention relates to the use of the relative value of the gene expression level of the gene for ADIPOQ and/or of a gene, the expression of which has linear statistical correlation with that of the ADIPOQ gene, in the prognosis or the diagnosis of a type II diabetes mellitus disease in a test subject. It further relates to a method for prognosing and/or diagnosing a type II diabetes mellitus disease for classification of a subject into risk groups, wherein the gene expression level of the ADIPOQ gene and/or of a gene, the expression of which has linear statistical correlation with that of the ADIPOQ gene, is determined and the subject is subsequently classified into risk groups, taking said gene expression level into account.
Type:
Application
Filed:
November 19, 2018
Publication date:
December 3, 2020
Applicant:
Lipozyt Marker UG
Inventors:
Uwe JENSEN, Wolfgang HIERNEIS, Markus KLEMKE, Helge Wilhelm THIES
Abstract: The invention relates to a method for the prognosis of adiposity and the prognosis and/or diagnosis of a disease selected from the group consisting of diabetes, cardiovascular diseases and metabolic syndrome.